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Share-Based Payments (Tables)
9 Months Ended
Sep. 30, 2016
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Schedule of Stock-Based Compensation Costs
Stock-based compensation costs included in the consolidated statements of operations are presented below:
 
Three Months Ended 
 September 30,
 
Nine Months Ended 
 September 30,
 
2016
 
2015
 
2016
 
2015
Cost of products
$
21

 
$
21

 
$
61

 
$
76

Cost of services
68

 
98

 
206

 
301

Research and development
2,236

 
2,234

 
6,979

 
6,141

Selling, general and administrative
8,467

 
6,032

 
23,385

 
20,006

Total
$
10,792

 
$
8,385

 
$
30,631

 
$
26,524

Schedule of Stock Option Activity
Stock option activity was as follows:
 
Number of Shares
 
Weighted Average Exercise Price
 
Weighted Average Remaining Contractual Term (Years)
Balances at December 31, 2015
11,043,528

 
$
32.66

 
8.49
Granted
4,384,860

 
29.42

 
 
Exercised
(1,162,843
)
 
(15.63
)
 
 
Forfeited
(2,127,334
)
 
(43.29
)
 
 
Expired
(34,804
)
 
(35.76
)
 
 
Balances at September 30, 2016
12,103,407

 
31.24

 
8.50
Exercisable at September 30, 2016
3,369,252

 
27.99

 
7.25
Vested and Expected to Vest at September 30, 2016(1)
10,177,058

 
30.99

 
8.37
(1)
The number of stock options expected to vest takes into account an estimate of expected forfeitures.