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Related Party Transactions (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
Sep. 30, 2016
Jun. 30, 2016
Nov. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Dec. 31, 2015
Related Party Transaction [Line Items]                
Shares issued as payment for services           $ 8,284    
Fair value of financial assets measured at fair value on a recurring basis $ 376,093     $ 376,093   376,093   $ 291,762
Collaboration and licensing revenues       30,590 $ 34,726 82,144 $ 66,690  
Third Security, LLC                
Related Party Transaction [Line Items]                
Expense for services       $ 156 142 $ 301 294  
Initial term of services agreement     1 year          
Shares issued as payment for services (in shares)       89,326   254,496    
Shares issued as payment for services       $ 2,132   $ 6,542    
Third Security, LLC | Common Stock                
Related Party Transaction [Line Items]                
Expense for services     $ 800          
Fibrocell Science, Inc.                
Related Party Transaction [Line Items]                
Payments to acquire convertible notes and warrants $ 2,604              
Oragenics, Inc.                
Related Party Transaction [Line Items]                
Common stock purchased from collaborative partners, shares   2,261,419            
Price per share of common shares (usd per share)   $ 0.52            
Oragenics, Inc. | Maximum                
Related Party Transaction [Line Items]                
Maximum percentage of shares of future securities offerings of collaborative partners to which the entity is entitled to purchase 30.00%     30.00%   30.00%    
Related Parties, Aggregated                
Related Party Transaction [Line Items]                
Collaboration and licensing revenues       $ 26,688 31,740 $ 70,299 59,775  
Harvest Intrexon Enterprise Fund I, LP | Other nonoperating income                
Related Party Transaction [Line Items]                
Management fees revenue       613 $ 697 1,871 $ 697  
Convertible Note and Warrants | Other Assets | Fibrocell Science, Inc.                
Related Party Transaction [Line Items]                
Fair value of financial assets measured at fair value on a recurring basis $ 1,990     $ 1,990   $ 1,990