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Shareholders' Equity - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands | 1 Months Ended | 12 Months Ended
--- | --- | ---
Aug. 31, 2015 | Jun. 30, 2015 | Jan. 31, 2015 | Mar. 31, 2014 | Dec. 31, 2016 | Dec. 31, 2015 | Dec. 31, 2014
Class of Stock [Line Items] |  |  |  |  |  |  |
Shares issued in public or private offerings, shares | 5,609,756 |  | 4,312,500 | 972,004 |  |  |
Value of shares issued in public or private offerings | $ 218,193 |  | $ 110,041 |  |  | $ 328,234 | $ 25,000
Underwriting discounts and commissions | 11,500 |  | 6,086 |  |  |  |
Capitalized offering expenses | $ 306 |  | $ 311 |  |  |  |
Proceeds from issuance of shares in a private placement |  |  |  | $ 25,000 | $ 0 | 0 | $ 25,000
Affiliates Of Third Security |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |
Shares issued in public or private offerings, shares |  |  | 555,556 | 243,001 |  |  |
Value of shares issued in public or private offerings |  |  |  | $ 6,250 |  |  |
ZIOPHARM Oncology, Inc. |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |
Noncash dividend, shares |  | 17,830,305 |  |  |  |  |
Realized investment gain |  |  |  |  |  | $ 81,401 |
Intrexon Stock Option Plans |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |
Adjustment due to dividend (in shares) |  |  |  |  |  | 312,795 |
Adjustment due to dividend (in usd per share) |  |  |  |  |  | $ 25.40 |

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