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Summary of Significant Accounting Policies - Additional Information (Details) $ in Thousands | 3 Months Ended | 12 Months Ended
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Dec. 31, 2016 USD ($) | Sep. 30, 2016 USD ($) | Jun. 30, 2016 USD ($) | Mar. 31, 2016 USD ($) | Dec. 31, 2015 USD ($) | Sep. 30, 2015 USD ($) | Jun. 30, 2015 USD ($) | Mar. 31, 2015 USD ($) | Dec. 31, 2016 USD ($) segment | Dec. 31, 2015 USD ($) | Dec. 31, 2014 USD ($)
Organization And Significant Accounting Policies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Research and development commitments with third parties not incurred | $ 10,631 |  |  |  | $ 4,138 |  |  |  | $ 10,631 | $ 4,138 |
Maturity period of highly liquid investment |  |  |  |  |  |  |  |  | 3 months |  |
Cash equivalent investments in highly liquid money market accounts | 43,808 |  |  |  | 112,776 |  |  |  | $ 43,808 | 112,776 |
Fair value of financial assets measured at fair value on a recurring basis | 335,307 |  |  |  | 291,762 |  |  |  | 335,307 | 291,762 |
Unrealized and realized appreciation (depreciation) in fair value of equity securities and preferred stock |  |  |  |  |  |  |  |  | (58,894) | 66,876 | $ (10,469)
Maximum risk of loss related to the identified VIEs | 159,115 |  |  |  | 3,598 |  |  |  | $ 159,115 | 3,598 |
Number of segments | segment |  |  |  |  |  |  |  |  | 1 |  |
Property, plant and equipment, net | 64,672 |  |  |  | 42,739 |  |  |  | $ 64,672 | 42,739 |
Revenues | $ 46,002 | $ 48,985 | $ 52,501 | $ 43,438 | $ 41,498 | $ 53,367 | $ 44,891 | $ 33,849 | $ 190,926 | $ 173,605 | 71,930
Oragenics, Inc. |  |  |  |  |  |  |  |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Company's ownership percentage | 29.50% |  |  |  | 30.70% |  |  |  | 29.50% | 30.70% |
ZIOPHARM Oncology, Inc. |  |  |  |  |  |  |  |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Realized investment gain |  |  |  |  |  |  |  |  |  | $ 81,401 |
Equity securities |  |  |  |  |  |  |  |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Fair value of financial assets measured at fair value on a recurring basis | $ 23,522 |  |  |  | $ 83,653 |  |  |  | $ 23,522 | 83,653 |
Equity securities | Oragenics, Inc. |  |  |  |  |  |  |  |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Fair value of financial assets measured at fair value on a recurring basis | 7,244 |  |  |  | 16,601 |  |  |  | 7,244 | 16,601 |
Unrealized and realized appreciation (depreciation) in fair value of equity securities and preferred stock |  |  |  |  |  |  |  |  | (10,523) | 4,863 | (14,969)
Equity securities | ZIOPHARM Oncology, Inc. |  |  |  |  |  |  |  |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Unrealized and realized appreciation (depreciation) in fair value of equity securities and preferred stock |  |  |  |  |  |  |  |  |  |  | 11,965
Foreign Countries |  |  |  |  |  |  |  |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Property, plant and equipment, net | $ 13,265 |  |  |  | $ 3,877 |  |  |  | 13,265 | 3,877 |
Revenues |  |  |  |  |  |  |  |  | $ 11,969 | $ 5,918 | $ 2,166
Minimum |  |  |  |  |  |  |  |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Expected useful life of intangible asset |  |  |  |  |  |  |  |  | 2 years |  |
Maximum |  |  |  |  |  |  |  |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Expected useful life of intangible asset |  |  |  |  |  |  |  |  | 21 years |  |
Intrexon Stock Option Plans |  |  |  |  |  |  |  |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |  |  |  |  |  |  |  |
Expected dividend yield |  |  |  |  |  |  |  |  | 0.00% | 0.00% | 0.00%

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