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Consolidated Statements of Operations (Parenthetical) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Related Party Transaction [Line Items]    
Revenues $ 23,335 $ 39,666
Collaboration and licensing agreements    
Related Party Transaction [Line Items]    
Revenues 5,970 19,848
Collaboration and licensing agreements | Related Parties, Aggregated    
Related Party Transaction [Line Items]    
Revenues $ 3,812 $ 16,640