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Property, Plant and Equipment, Net - Schedule of Property, Plant and Equipment (Details) - USD ($) $ in Thousands	Mar. 31, 2019	Dec. 31, 2018
Property, Plant and Equipment [Abstract]
Land and land improvements	$ 12,475	$ 12,490
Buildings and building improvements	20,387	20,371
Furniture and fixtures	1,891	1,891
Equipment	76,716	74,555
Leasehold improvements	31,271	28,289
Breeding stock	4,603	4,582
Computer hardware and software	11,852	11,697
Trees	12,076	11,910
Construction and other assets in progress	24,123	18,880
Property, plant and equipment, gross	195,394	184,665
Less: Accumulated depreciation and amortization	(59,037)	(55,791)
Property, plant and equipment, net	$ 136,357	$ 128,874

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Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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Amount before accumulated depreciation of equipment commonly used in offices and stores that have no permanent connection to the structure of a building or utilities. Examples include, but are not limited to, desks, chairs, tables, and bookcases.

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