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v3.19.3

Segments - Reconciliation of Net Loss Before Income Taxes (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2019 | Sep. 30, 2018 | Sep. 30, 2019 | Sep. 30, 2018
Segment Reporting Information [Line Items] |  |  |  |
Segment Adjusted EBITDA | $ (33,242) | $ (32,556) | $ (102,247) | $ (93,698)
Other expenses: |  |  |  |
Interest expense | (4,471) | (3,999) | (13,140) | (4,240)
Depreciation and amortization |  |  | (18,711) | (25,184)
Impairment loss | (626) | 0 | (626) | 0
Stock-based compensation expense | (5,423) | (8,132) | (14,538) | (28,340)
Equity in net loss of affiliates | (1,647) | (2,870) | (5,034) | (9,880)
Other |  |  | (3,284) | (635)
Loss before income taxes | (54,146) | (73,068) | (156,316) | (192,519)
Operating segments |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |
Remove cash paid for capital expenditures and investments in affiliates | 8,115 | 10,373 | 34,021 | 30,422
Corporate And Reconciling Items |  |  |  |
Other expenses: |  |  |  |
Interest expense | (4,471) | (3,999) | (13,140) | (4,240)
Depreciation and amortization | (6,021) | (8,303) | (18,711) | (25,184)
Impairment loss | (626) | 0 | (626) | 0
Reacquisition of in-process research and development | 0 | (8,721) | 0 | (8,721)
Stock-based compensation expense | (5,423) | (8,132) | (14,538) | (28,340)
Equity in net loss of affiliates | (1,647) | (2,870) | (5,034) | (9,880)
Other | 35 | 0 | 35 | 0
Unallocated corporate costs |  |  |  |
Other expenses: |  |  |  |
Loss before income taxes | (13,544) | (25,440) | (43,657) | (75,319)
Eliminations |  |  |  |
Other expenses: |  |  |  |
Loss before income taxes | (3,092) | (621) | (9,104) | (1,659)
Reportable segments |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |
Segment Adjusted EBITDA | (24,716) | (23,502) | (76,227) | (62,610)
All Other |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |
Segment Adjusted EBITDA | (8,526) | (9,054) | (26,020) | (31,088)
Upfront and Milestone Payments | Operating segments |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |
Add recognition of previously deferred revenue associated with upfront and milestone payments | $ 5,770 | $ 7,201 | $ 16,685 | $ 24,100

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