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Segments - Reconciliation of Net Loss Before Income Taxes (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2020
Jun. 30, 2019
Jun. 30, 2020
Jun. 30, 2019
Segment Reporting Information [Line Items]        
Segment Adjusted EBITDA $ (5,362) $ (18,680) $ (25,080) $ (40,200)
Other expenses:        
Depreciation and amortization     (9,593) (12,690)
Stock-based compensation expense (4,897) (61) (9,269) (9,115)
Equity in net loss of affiliates     (640) (3,387)
Other     112 (3,141)
Loss before income taxes (43,474) (32,314) (73,376) (85,227)
Operating segments        
Segment Reporting Information [Line Items]        
Remove cash paid for capital expenditures and investments in affiliates 1,879 4,155 4,620 7,667
Operating segments | Upfront And Milestone Payments [Member]        
Segment Reporting Information [Line Items]        
Add recognition of previously deferred revenue associated with upfront and milestone payments 5,573 6,247 18,046 10,859
Corporate And Reconciling Items        
Other expenses:        
Interest expense (4,592) (4,353) (9,184) (8,658)
Depreciation and amortization (4,783) (4,863) (9,593) (10,207)
Impairment losses (22,041) 0 (22,041) 0
Stock-based compensation expense (4,897) 484 (10,615) (7,764)
Adjustment related to bonuses paid in equity awards 0 0 2,833 0
Equity in net loss of affiliates (251) (716) (602) (1,464)
Other 3 0 12 0
Unallocated corporate costs        
Other expenses:        
Loss before income taxes (7,344) (11,426) (17,526) (29,448)
Eliminations        
Other expenses:        
Loss before income taxes (1,659) (3,162) (4,246) (6,012)
Segment Adjusted EBITDA for reportable segments        
Segment Reporting Information [Line Items]        
Segment Adjusted EBITDA (5,999) (16,201) (26,209) (36,483)
All Other        
Segment Reporting Information [Line Items]        
Segment Adjusted EBITDA $ 637 $ (2,479) $ 1,129 $ (3,717)