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v3.20.4

Related Party Transactions - Additional Information (Details) | 1 Months Ended | 10 Months Ended | 12 Months Ended |
--- | --- | --- | --- | ---
Jan. 31, 2020 USD ($) | Dec. 31, 2019 USD ($) | Oct. 31, 2019 USD ($) | Jan. 31, 2018 shares | Jul. 31, 2018 shares | Dec. 31, 2020 USD ($) | Dec. 31, 2019 USD ($) shares | Dec. 31, 2018 USD ($) relatedParty shares | Oct. 31, 2017 USD ($)
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |
Shares issued as payment for services |  |  |  |  |  |  | $ 10,446,000 | $ 10,695,000 |
Shares issued during the period (in shares) | shares |  |  |  | 6,900,000 |  |  |  |  |
Dividend income from investments in preferred stock |  |  |  |  |  | $ 0 | 48,000 | 14,841,000 |
Proceeds from sales of equity securities |  |  | $ 21,587,000 |  |  | 0 | 23,456,000 | 217,000 |
Receivables |  | $ 2,030,000 |  |  |  | 232,000 | 2,030,000 |  |
Third Security |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |
Expense for services |  |  |  |  |  | 159,000 | $ 26,000 | $ 47,000 |
Common stock calculation period |  |  |  |  |  |  | 30 days |  |
Shares issued as payment for services, shares | shares |  |  |  |  |  |  | 1,606,062 | 696,033 |
Shares issued as payment for services |  |  |  |  |  |  | $ 8,233,000 | $ 8,324,000 |
Sublease rental income |  |  |  |  |  | $ 83,000 | 89,000 |  |
Sublease rental income |  |  |  |  |  |  |  | 89,000 |
Affiliates of Third Security |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |
Shares issued during the period (in shares) | shares |  |  |  | 1,000,000 |  |  |  |  |
Castle Creek Biosciences, Inc. |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |
Proceeds from sales of equity securities |  | 1,280,000 |  |  |  |  |  |  |
Proceeds from Convertible Preferred Shares and convertible note | $ 3,311,000 |  |  |  |  |  |  |  |
Receivables |  | $ 3,311,000 |  |  |  |  | 3,311,000 |  |
Changes in fair value, gain |  |  |  |  |  |  | 3,222,000 |  |
Common Stock | Third Security |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |
Expense for services |  |  |  |  |  |  | $ 800,000 |  |
Series A Preferred Shares |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |
Shares issued during the period (in shares) | shares |  |  |  |  | 0 |  |  |  |
Series A Preferred Shares | Affiliates of Third Security |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |
Convertible preferred stock, amount authorized |  |  |  |  |  |  |  |  | $ 100,000,000
Third Security | Executive Chairman |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |
Ownership interest |  |  |  |  |  | 100.00% |  |  |
ZIOPHARM Oncology, Inc. |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |
Dividend income from investments in preferred stock |  |  |  |  |  |  |  | $ 14,793,000 |
Collaboration and licensing agreements | Various ECC Agreements |  |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |  |
Number of related parties with terminated agreements | relatedParty |  |  |  |  |  |  |  | 3 |
Revenue recognized from previously deferred balances |  |  |  |  |  |  |  | $ 11,877,000 |

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