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v3.20.4

Segments - Reconciliation of Net Loss Before Income Taxes (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018
Segment Reporting Information [Line Items] |  |  |
Segment Adjusted EBITDA | $ (28,713) | $ (56,115) | $ (62,067)
Other expenses: |  |  |
Depreciation and amortization | (17,516) | (24,896) | (33,112)
Loss on settlement agreement | (11,436) | 0 | 0
Stock-based compensation expense | (18,366) | (18,950) | (36,296)
Equity in net loss of affiliates | (1,176) | (6,730) | (11,608)
Other | (226) | (837) | (1,093)
Loss from continuing operations before income taxes | (103,855) | (171,264) | (395,912)
Operating segments |  |  |
Segment Reporting Information [Line Items] |  |  |
Remove cash paid for capital expenditures and investments in affiliates | 6,970 | 12,512 | 15,276
Other expenses: |  |  |
Other expenses: |  |  |
Interest expense | (18,400) | (17,666) | (8,473)
Depreciation and amortization | (15,042) | (16,142) | (20,612)
Impairment losses | (920) | (30,810) | 0
Reacquisition of in-process research and development | 0 | 0 | (236,748)
Loss on settlement agreement | (11,436) | 0 | 0
Stock-based compensation expense | (19,746) | (15,098) | (30,554)
Adjustment related to accrued bonuses paid in equity awards | 2,833 | 0 | 0
Equity in net loss of affiliates | (1,138) | (2,416) | (8,986)
Other | 11 | 67 | 0
Unallocated corporate costs |  |  |
Other expenses: |  |  |
Loss from continuing operations before income taxes | (37,566) | (46,011) | (74,609)
Eliminations |  |  |
Other expenses: |  |  |
Loss from continuing operations before income taxes | (5,713) | (14,306) | (2,343)
Reportable segments |  |  |
Segment Reporting Information [Line Items] |  |  |
Segment Adjusted EBITDA | (32,987) | (51,214) | (51,359)
All Other |  |  |
Segment Reporting Information [Line Items] |  |  |
Segment Adjusted EBITDA | 4,274 | (4,901) | (10,708)
Upfront and Milestone Payments | Operating segments |  |  |
Segment Reporting Information [Line Items] |  |  |
Add recognition of previously deferred revenue associated with upfront and milestone payments | $ 25,005 | $ 14,721 | $ 33,204

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