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Share-Based Payments (Tables)

12 Months Ended

Dec. 31, 2020

Share-based Payment Arrangement [Abstract]

Schedule of Stock-based Compensation Expense

Stock-based compensation costs included in the consolidated statements of operations are presented below:

			Year Ended December 31,
			2020						2019						2018
Cost of products			$	10					$	20					$	78
Cost of services			134						220						237
Research and development			1,815						3,478						5,017
Selling, general and administrative			17,787						11,380						25,222
Discontinued operations			(1,380)						3,852						5,742
Total			$	18,366					$	18,950					$	36,296

Schedule of Stock Option Activity

Stock option activity was as follows:

			Number of Shares						Weighted Average Exercise Price						Weighted Average Remaining Contractual Term (Years)
Balances at December 31, 2017			11,382,747						$	28.99					7.32
Granted			1,470,339						14.26
Exercised			(45,159)						(6.59)
Forfeited			(929,596)						(21.48)
Expired			(785,268)						(26.25)
Balances at December 31, 2018			11,093,063						27.95						6.81
Granted			1,556,575						6.52
Exercised			(19,887)						(3.17)
Forfeited			(1,236,326)						(24.92)
Expired			(2,371,143)						(38.53)
Balances at December 31, 2019			9,022,282						21.94						6.10
Granted			5,693,498						10.03
Exercised			(30,061)						(3.88)
Forfeited			(976,324)						(15.47)
Expired			(2,453,499)						(26.53)
Balances at December 31, 2020			11,255,896						15.53						7.25
Exercisable at December 31, 2020			5,437,667						19.61						5.61

Summary of Information About Stock Options Outstanding

The following table summarizes additional information about stock options outstanding as of December 31, 2020:

												Options Outstanding																								Options Exercisable
Range of Exercise Prices												Number of Options						Weighted Average Exercise Price						Weighted Average Remaining Life (Years)						Aggregate Intrinsic Value						Number of Options						Weighted Average Exercise Price						Weighted Average Remaining Life (Years)						Aggregate Intrinsic Value
$	1.55		—			$	5.95					3,259,685						$	4.63					8.92						$	18,157					1,271,310						$	3.11					8.73						$	9,018
$	6.06		—			$	15.09					2,261,216						11.01						8.23						1,325						345,788						9.09						4.76						689
$	15.80		—			$	20.94					3,028,309						18.85						7.38						—						1,216,258						19.82						5.62						—
$	21.13		—			$	36.84					2,303,371						26.33						4.32						—						2,200,996						26.52						4.22						—
$	37.88		—			$	47.35					403,315						42.26						4.01						—						403,315						42.26						4.01						—
												11,255,896						$	15.53					7.25						$	19,482					5,437,667						$	19.61					5.61						$	9,707

The following table summarizes additional information about stock options outstanding as of December 31, 2019:

												Options Outstanding																								Options Exercisable
Range of Exercise Prices												Number of Options						Weighted Average Exercise Price						Weighted Average Remaining Life (Years)						Aggregate Intrinsic Value						Number of Options						Weighted Average Exercise Price						Weighted Average Remaining Life (Years)						Aggregate Intrinsic Value
$	3.17		—			$	8.60					1,612,219						$	6.40					8.08						$	473					585,144						$	5.61					5.95						$	194
$	8.77		—			$	20.68					1,278,121						15.55						6.53						—						753,064						15.89						5.20						—
$	20.94											1,646,500						20.94						6.51						—						892,000						20.94						6.02						—
$	21.00		—			$	29.47					1,976,645						23.71						6.06						—						1,585,940						23.71						5.79						—
$	29.56		—			$	65.08					2,508,797						34.46						4.38						—						2,448,046						34.47						4.33						—
												9,022,282						$	21.94					6.10						$	473					6,264,194						$	24.89					5.20						$	194

Schedule of Restricted Stock Unit Activity

RSU activity was as follows:

			Number of Restricted Stock Units						Weighted Average Grant Date Fair Value						Weighted Average Remaining Contractual Term (Years)
Balances at December 31, 2017			—						$	—					0.00
Granted			1,069,126						13.84
Vested			(25,000)						(15.82)
Forfeited			(73,785)						(13.47)
Balances at December 31, 2018			970,341						13.82						1.43
Granted			2,278,460						6.59
Vested			(1,159,165)						(8.74)
Forfeited			(307,654)						(8.99)
Balances at December 31, 2019			1,781,982						8.71						1.24
Granted			3,157,390						3.09
Vested			(2,802,593)						(3.99)
Forfeited			(409,067)						(8.59)
Balances at December 31, 2020			1,727,712						6.11						0.42

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