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Related Party Transactions - Additional Information (Details) - USD ($) $ in Thousands | 1 Months Ended | 3 Months Ended | 9 Months Ended
--- | --- | --- | ---
Jan. 31, 2020 | Dec. 31, 2019 | Sep. 30, 2021 | Sep. 30, 2020 | Sep. 30, 2021 | Sep. 30, 2020
Third Security, LLC |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |
Expense for services |  |  | $ 43 | $ 56 | $ 89 | $ 132
Sublease rental income |  |  | $ 20 | $ 18 | $ 61 | $ 64
Castle Creek Biosciences, Inc. |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |
Proceeds from sale and maturity of other investments |  | $ 1,280 |  |  |  |
Proceeds from convertible notes receivable and investment in preferred stock | $ 3,311 |  |  |  |  |
Third Security, LLC | Executive Chairman |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |
Ownership interest |  |  | 100.00% |  | 100.00% |

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- Definition Amount of sublease income excluding finance and operating lease expense. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 842 -SubTopic 20 -Section 50 -Paragraph 4 -Subparagraph (e) -URI http://asc.fasb.org/extlink&oid=123408670&loc=SL77918686-209980 Reference 2: http://www.xbrl.org/2003/role/exampleRef -Publisher FASB -Name Accounting Standards Codification -Topic 842 -SubTopic 20 -Section 55 -Paragraph 53 -URI http://asc.fasb.org/extlink&oid=123414884&loc=SL77918982-209971 + Details
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