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Goodwill and Intangible Assets, Net | 9 Months Ended
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Sep. 30, 2022
Goodwill and Intangible Assets Disclosure [Abstract] |
Goodwill and Intangible Assets, Net | Goodwill and Intangible Assets, Net The changes in the carrying amount of goodwill for the nine months ended September 30, 2022 were as follows:
Balance at December 31, 2021 | $ | 37,554 |
Impairment | (482) |
Foreign currency translation adjustments | (359) |
Balance at September 30, 2022 | $ | 36,713 |
The Company recorded $482 of goodwill impairment related to the total goodwill assigned to one reporting unit within the biopharmaceutical segment during the first quarter of 2022. The Company had $14,483 and $14,001 of cumulative impairment losses as of September 30, 2022 and December 31, 2021, respectively. Intangible assets consist of the following as of September 30, 2022:
| Gross Carrying Amount |  | Accumulated Amortization |  | Net
Patents, developed technologies and know-how | $ | 75,129 |  |  | $ | (32,713) |  |  | $ | 42,416 |
Customer relationships | 1,600 |  |  | (1,600) |  |  | — |
Trademarks | 200 |  |  | (200) |  |  | — |
Total | $ | 76,929 |  |  | $ | (34,513) |  |  | $ | 42,416 |
Intangible assets consist of the following as of December 31, 2021:
| Gross Carrying Amount |  | Accumulated Amortization |  | Net
Patents, developed technologies and know-how | $ | 85,173 |  |  | $ | (32,882) |  |  | $ | 52,291 |
Customer relationships | 1,600 |  |  | (1,600) |  |  | — |
Trademarks | 200 |  |  | (200) |  |  | — |
Total | $ | 86,973 |  |  | $ | (34,682) |  |  | $ | 52,291 |
Amortization expense was $1,151 and $1,315 for the three months ended September 30, 2022 and 2021, respectively, and $3,637 and $3,990 for the nine months ended September 30, 2022 and 2021, respectively.

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- Definition The entire disclosure for goodwill and intangible assets. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -URI https://asc.fasb.org/topic&trid=2144416 + Details
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