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Merger and Related Transactions (Details)
$ in Thousands
 12 Months Ended
Mar. 21, 2024
USD ($)
member
shares
Dec. 31, 2025
USD ($)
Dec. 31, 2024
USD ($)
Reverse Recapitalization [Line Items]      
Number of board of directors, former stockholders | member 5    
Number of board of directors, combined company | member 7    
Issuance of common stock from private placement, net (in shares) | shares 8,670,653    
Recapitalization exchange ratio 0.2022    
Sale of stock, number of shares issued (in shares) | shares 15,409,102    
Sale of stock, consideration received $ 53,500    
Sale of stock, percentage of ownership following transaction 56.00%    
Cash and cash equivalents acquired $ 112,600    
Assets acquired 1,500    
Payables and accruals acquired 3,200    
Merger transaction costs $ 5,200   $ 5,070
Acceleration of stock awards, expense   $ 300  
Graphite Bio, Inc. Stockholders      
Reverse Recapitalization [Line Items]      
Sale of stock, percentage of ownership following transaction 31.00%    
PIPE Investors      
Reverse Recapitalization [Line Items]      
Sale of stock, percentage of ownership following transaction 13.00%