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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2024
Table Text Block Supplement [Abstract]  
Schedule of Income Taxes
Income taxes consisted of the following for the periods presented (in thousands):
 
    
Year Ended December 31,
 
    
 2024 
    
 2023 
 
Current:
     
Federal
   $    —       $    —   
State
     1        9  
  
 
 
    
 
 
 
Total
     1        9  
  
 
 
    
 
 
 
Deferred:
     
Federal
     —         —   
State
     —         —   
  
 
 
    
 
 
 
Total
     —         —   
  
 
 
    
 
 
 
Income taxes
   $ 1      $ 9  
  
 
 
    
 
 
 
Schedule of effective income tax rate reconciliation
The Company’s effective income tax rate reconciliation was composed of the following for the periods presented (in thousands):
 
    
Year Ended December 31,
 
    
 2024 
    
 2023 
 
Federal statutory rate, benefit
   $ (14,586    $ (11,958
State income taxes, net of benefit
     (5,318      (4,881
Nondeductible expenses
     35        153  
Stock-based compensation
     2,566        1,618  
Change in valuation allowance
     20,366        18,099  
R&D credits
     (3,084      (3,022
Other
     22        —   
  
 
 
    
 
 
 
Income taxes
   $ 1      $ 9  
  
 
 
    
 
 
 
Schedule of net deferred tax assets
Deferred Income Taxes
The components of net deferred tax assets were as follows for the periods presented (in thousands):
 
    
December 31,
 
    
2024
    
2023
 
Deferred tax assets:
     
Net operating loss carryforwards
   $ 47,448      $ 35,486  
Accrued expenses and other current liabilities
     1,666        1,212  
Charitable contributions
     22        8  
Depreciation and amortization
     930        756  
Stock-based compensation
     233        —   
Operating lease liabilities
     2,136        1,848  
Capitalized research and development expense
     12,920        8,659  
Tenant improvement allowance
     —         4  
Section 195 capitalization
     369        418  
Research and development credits
     12,076        8,764  
  
 
 
    
 
 
 
Total deferred tax assets
     77,800        57,155  
Less: valuation allowance
     (75,737      (55,372
  
 
 
    
 
 
 
Total deferred tax assets, net of valuation allowance
     2,063        1,783  
  
 
 
    
 
 
 
Deferred tax liabilities:
     
Operating lease
right-of-use
assets
     (2,064      (1,784
Other
     1        1  
  
 
 
    
 
 
 
Total deferred tax liabilities
     (2,063      (1,783
  
 
 
    
 
 
 
Net deferred tax assets
   $ —       $ —   
  
 
 
    
 
 
 
Schedule of tax credit carryforwards
Available Carryforwards
As of December 31, 2024, NOLs and tax credit carryforwards were as follows (in millions):
 
    
Amount
    
Expiration Years
NOLs, federal
   $  160.8      Indefinite
NOLs, state
     154.3      2039
Research and development tax credits, federal
     9.4      2039
Research and development tax credits, state
     6.7      Indefinite
Schedule of unrecognized tax benefits
Uncertain Tax Positions
A reconciliation of the beginning and ending balance of total gross unrecognized tax benefits was as follows for the periods presented (in thousands):
 
    
December 31,
 
    
2024
    
2023
 
Beginning balance of unrecognized tax benefits
   $  2,441      $  1,679  
Gross increases based on tax positions related to current year
     795        762  
Gross increases based on tax positions related to prior years
     33        —   
  
 
 
    
 
 
 
Ending balance of unrecognized tax benefits
   $ 3,269      $ 2,441