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Issued Capital and Reserves - Impact of share split (Details)
€ in Thousands, $ in Millions
 1 Months Ended 3 Months Ended 9 Months Ended
Sep. 30, 2022
USD ($)
shares
Sep. 30, 2021
USD ($)
Sep. 30, 2022
shares
Jun. 30, 2022
shares
Mar. 31, 2022
shares
Sep. 30, 2022
USD ($)
shares
Sep. 30, 2021
EUR (€)
Issued Capital and Reserves              
Common shares issued and outstanding beginning     187,466,954 187,120,728 187,120,728 187,120,728  
Share option exercises       39,418 78,732    
Treasury shares       (39,418) (78,732)    
Share issuances for exercises     9,746 6,211      
Share issuances to former shareholders of Frame Pharmaceuticals     858,496        
At-the-market offering program issuances     1,948,040 340,015      
Common shares issued and outstanding ending 190,283,236   190,283,236 187,466,954 187,120,728 190,283,236  
Cash received from issuance of shares $ 32.7           € 404,164
Shares issue of transaction costs | $           $ 1.0  
ATM Offering Program              
Issued Capital and Reserves              
At-the-market offering program issuances 2,288,055            
Aggregate gross proceeds | $   $ 600.0