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Share-based payments - Long-Term Incentive Plan (LTIP) (Details)
1 Months Ended 12 Months Ended
Apr. 01, 2023
Option
Mar. 31, 2023
shares
Apr. 01, 2022
Option
€ / shares
Mar. 31, 2022
Mar. 01, 2022
$ / shares
Jan. 01, 2022
Option
€ / shares
Aug. 01, 2021
Option
Jul. 01, 2021
Option
€ / shares
Mar. 01, 2021
Option
€ / shares
Dec. 01, 2020
Option
Nov. 16, 2020
Option
€ / shares
Jan. 31, 2022
Dec. 31, 2023
Option
Dec. 31, 2022
Option
€ / shares
Dec. 31, 2022
$ / shares
Apr. 01, 2022
$ / shares
Jan. 01, 2022
$ / shares
Dec. 31, 2021
€ / shares
Dec. 31, 2021
$ / shares
Jul. 01, 2021
$ / shares
Mar. 01, 2021
$ / shares
Nov. 16, 2020
$ / shares
Share-based payments                                            
Exercise price of options granted | $ / shares         $ 19.35                                  
Vesting percentage (as a percent)         25.00%                                  
Number of days increase related to percentage of stock price                         10 days                  
LTIP Stock Options                                            
Share-based payments                                            
Number of share options granted         130,000                                  
LTIP Stock Options | Chief Scientific Officer                                            
Share-based payments                                            
Number of share options granted         25,000           266,155                      
Exercise price of options granted | € / shares                     € 10.04                      
Threshold duration of volume weighted average price                     10 days                      
Vesting period (in years)                     4 years                      
Vesting percentage (as a percent)                     25.00%                      
Percentage of increase in share price                     20.00%                      
Exercised during the period                         0 (6,303)                
LTIP Stock Options | Chief Business Officer and Chief Commercial Officer                                            
Share-based payments                                            
Number of share options granted         25,000         266,156                        
Vesting period (in years)                     10 years                      
Percentage of increase in share price                     10.00%                      
Number of days increase related to percentage of stock price                           10 days                
LTIP Stock Options | Chief Business Officer and Chief Commercial Officer | Minimum                                            
Share-based payments                                            
Vesting period (in years)                     1 year                      
LTIP Stock Options | Chief Business Officer and Chief Commercial Officer | Maximum                                            
Share-based payments                                            
Vesting period (in years)                     3 years                      
LTIP Stock Options | Chief Business Officer and Chief Commercial Officer | First tranche                                            
Share-based payments                                            
Exercise price of options granted | (per share)                     € 43.87     € 81.65 $ 98.57     € 81.48 $ 98.36     $ 52.96
LTIP Stock Options | Chief Business Officer and Chief Commercial Officer | Second tranche                                            
Share-based payments                                            
Exercise price of options granted | (per share)                                   € 33.07 $ 39.92      
LTIP Stock Options | Chief Business Officer and Chief Commercial Officer | Third tranche                                            
Share-based payments                                            
Exercise price of options granted | (per share)                           € 7.35 $ 7.68              
LTIP Stock Options | Key employees                                            
Share-based payments                                            
Number of share options granted     700     9,500     2,000                          
Exercise price of options granted | (per share)     € 17.45     € 30.67     € 77.73             $ 19.28 $ 33.87       $ 88.16  
Threshold duration of volume weighted average price     10 days 10 years   30 days     10 days                          
Vesting period (in years)     4 years     4 years     4 years                          
Vesting percentage (as a percent)     25.00%           25.00%     25.00%                    
Percentage of increase in share price     20.00%           10.00%     20.00%                    
Number of days increase related to percentage of stock price                       10 days                    
LTIP Stock Options | Chief Operating Officer                                            
Share-based payments                                            
Number of share options granted         25,000                                  
Exercise price of options granted | (per share)               € 70.92                       $ 84.03    
Threshold duration of volume weighted average price               20 days                            
Vesting period (in years)               4 years                            
Vesting percentage (as a percent)               25.00%                            
Percentage of increase in share price               20.00%                            
Number of days increase related to percentage of stock price               10 days                            
Exercised during the period               (20,000)                            
LTIP Stock Options | Chief Development Officer                                            
Share-based payments                                            
Exercise price of options granted | (per share)               € 46.16                       $ 54.79    
Vesting period (in years)               4 years                            
Vesting percentage (as a percent)               25.00%                            
Percentage of increase in share price               20.00%                            
Number of days increase related to percentage of stock price               10 days                            
Exercised during the period             (30,000)                              
LTIP Stock Options | Chief Financial Officer                                            
Share-based payments                                            
Number of share options granted         25,000                                  
LTIP Stock Options | the Chief Executive Officer                                            
Share-based payments                                            
Number of share options granted 144,379       30,000                                  
Restricted Stock Units                                            
Share-based payments                                            
Vesting percentage (as a percent)                         0.33%                  
Restricted Stock Units | LTIP Stock Options                                            
Share-based payments                                            
Vesting period (in years)                           3 years                
Vesting percentage (as a percent)                         0.33%                  
Restricted Stock Units | Members of supervisory board | LTIP Stock Options                                            
Share-based payments                                            
Number of share options granted | shares   92,701