v2.4.0.6

Consolidated Statements of Operations (USD $) In Thousands, except Per Share data, unless otherwise specified | 12 Months Ended
--- | ---
Dec. 31, 2011 | Dec. 31, 2010 | Dec. 31, 2009
Revenue (including amounts from a related party of $9,658 in 2011, $9,826 in 2010, and $15,073 in 2009) | $ 24,512 | $ 24,223 | $ 24,374
Operating expenses: |  |  |
Research and development | 103,568 | 75,070 | 77,524
General and administrative | 30,681 | 27,476 | 27,066
Restructuring charges |  |  | 1,145
Total operating expenses | 134,249 | 102,546 | 105,735
Loss from operations | (109,737) | (78,323) | (81,361)
Interest and other income | 415 | 505 | 2,111
Interest expense | (6,022) | (6,044) | (6,052)
Net loss | $ (115,344) | $ (83,862) | $ (85,302)
Basic and diluted net loss per share (in dollars per share) | $ (1.41) | $ (1.16) | $ (1.35)
Shares used in computing basic net loss per share (in shares) | 82,051 | 72,070 | 63,027
Shares used in computing diluted net loss per share (in shares) | 82,051 | 72,070 | 63,027

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