v2.4.0.6

Operating Leases and Subleases (Details) (USD $) | 12 Months Ended
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Dec. 31, 2011 Y sqft count building | Dec. 31, 2010 | Dec. 31, 2009
Operating Leases and Subleases |  |  |
Number of lease terms | 2 |  |
Additional lease period (in years) | 5 |  |
Number of buildings | 2 |  |
Area of building one in South San Francisco, California (in square feet) | 110,000 |  |
Area of building two in South San Francisco, California (in square feet) | 40,000 |  |
Future minimum lease payments |  |  |
2012 | $ 5,429,000 |  |
2013 | 5,029,000 |  |
2014 | 4,859,000 |  |
2015 | 5,005,000 |  |
2016 | 5,156,000 |  |
Thereafter | 18,806,000 |  |
Total | 44,284,000 |  |
Expenses and income associated with operating leases |  |  |
Rent expense | 6,702,000 | 6,779,000 | 6,559,000
Sublease income, net | (637,000) | (622,000) | (580,000)
Future minimum rental receivable under non-cancelable sublease | $ 200,000 |  |

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