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Description of Operations and Summary of Significant Accounting Policies - Description of Operations and Variable Interest Entity (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended |
--- | --- | --- | ---
Jun. 30, 2019 | Jun. 30, 2018 | Jun. 30, 2019 | Jun. 30, 2018 | Dec. 31, 2018
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |  |
Cash balance | $ 141,952 |  | $ 141,952 |  | $ 62,417 | [1]
Net revenue | 64,107 | $ 67,086 | 119,290 | $ 119,466 |  |
GSK |  |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |  |
Net revenue | 64,107 | 67,086 | $ 119,290 | 119,466 |  |
Long-Acting Beta2 Agonist (LABA) Collaboration | GSK |  |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |  |
Percentage of economic interest in any future payments made under the agreements |  |  | 15.00% |  |  |
Long-Acting Beta2 Agonist (LABA) Collaboration | GSK | RELVAR/BREO |  |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |  |
Royalty rate for first level of annual global net sales (as a percent) |  |  | 15.00% |  |  |
Annual global sales level used to determine royalty rate |  |  | $ 3,000,000 |  |  |
Royalty rate for sales above first level of annual global net sales (as a percent) |  |  | 5.00% |  |  |
Long-Acting Beta2 Agonist (LABA) Collaboration | GSK | ANORO | Minimum |  |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |  |
Royalty rate for combination products (as a percent) |  |  | 6.50% |  |  |
Long-Acting Beta2 Agonist (LABA) Collaboration | GSK | ANORO | Maximum |  |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |  |
Royalty rate for combination products (as a percent) |  |  | 10.00% |  |  |
TRC |  |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |  |
Cash balance | 13,800 |  | $ 13,800 |  |  |
TRC | TRELEGY |  |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |  |
Net revenue | 9,800 | $ 2,400 | 17,200 | $ 3,300 |  |
TRC | Collaborative arrangement |  |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |  |
Related-party receivables | $ 9,800 |  | $ 9,800 |  | $ 6,400 |
[1] | Condensed consolidated balance sheet as of December 31, 2018 has been derived from audited consolidated financial statements.

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