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Financial Instruments and Fair Value Measurements (Tables) | 3 Months Ended
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Mar. 31, 2021
Financial Instruments and Fair Value Measurements |
Schedule of amortized cost and estimated fair values for available-for-sale securities | Available-for-sale securities are summarized below: ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | March 31, 2021
​ | ​ | ​ | ​ | ​ | Gross | ​ | Gross | ​ | ​ | ​
​ | ​ | ​ | ​ | Unrealized | ​ | Unrealized | ​ | Estimated
(In thousands) |  | Amortized Cost |  | Gains |  | Losses |  | Fair Value
Money market funds(1) | ​ | $ | 248,932 | ​ | $ | — | ​ | $ | — | ​ | $ | 248,932
Total | ​ | $ | 248,932 | ​ | $ | — | ​ | $ | — | ​ | $ | 248,932
(1) | Money market funds were included in cash and cash equivalents on the consolidated balance sheets.
​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | December 31, 2020
​ | ​ | ​ | ​ | ​ | Gross | ​ | Gross | ​ | ​ | ​
​ | ​ | ​ | ​ | Unrealized | ​ | Unrealized | ​ | Estimated
(In thousands) |  | Amortized Cost |  | Gains |  | Losses |  | Fair Value
Money market funds (1) | ​ | $ | 204,808 | ​ | $ | — | ​ | $ | — | ​ | $ | 204,808
Total | ​ | $ | 204,808 | ​ | $ | — | ​ | $ | — | ​ | $ | 204,808
(1) | Money market funds were included in cash and cash equivalents on the consolidated balance sheets.
Schedule of available-for-sale securities measured at fair value on a recurring basis | The estimated fair values were as follows: ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Estimated Fair Value Measurements as of March 31, 2021 Using:
​ | ​ | Quoted Price | ​ | Significant | ​ | ​ | ​ | ​ | ​
​ | ​ | in Active | ​ | Other | ​ | Significant | ​ | ​ | ​
​ | ​ | Markets for | ​ | Observable | ​ | Unobservable | ​ | ​ | ​
Types of Instruments | ​ | Identical Assets | ​ | Inputs | ​ | Inputs | ​ | ​ | ​
(In thousands) |  | Level 1 |  | Level 2 |  | Level 3 |  | Total
Assets | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Money market funds | ​ | $ | 248,932 | ​ | $ | — | ​ | $ | — | ​ | $ | 248,932
Investments held by ISP Fund LP (1) | ​ | ​ | 304,696 | ​ | ​ | — | ​ | ​ | — | ​ | ​ | 304,696
Equity investment - Armata Common Stock | ​ | ​ | 71,053 | ​ | ​ | — | ​ | ​ | — | ​ | ​ | 71,053
Equity investment - Armata Warrants | ​ | ​ | — | ​ | ​ | 54,166 | ​ | ​ | — | ​ | ​ | 54,166
Equity investment - Entasis Common Stock | ​ | ​ | 39,960 | ​ | ​ | — | ​ | ​ | — | ​ | ​ | 39,960
Equity investment - Entasis Warrants | ​ | ​ | — | ​ | ​ | 26,580 | ​ | ​ | — | ​ | ​ | 26,580
Equity investment - InCarda Warrants | ​ | ​ | — | ​ | ​ | — | ​ | ​ | 664 | ​ | ​ | 664
Total assets measured at estimated fair value | ​ | $ | 664,641 | ​ | $ | 80,746 | ​ | $ | 664 | ​ | $ | 746,051
Debt | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
2023 Notes | ​ | $ | — | ​ | $ | 242,336 | ​ | $ | — | ​ | $ | 242,336
2025 Notes | ​ | ​ | — | ​ | ​ | 203,513 | ​ | ​ | — | ​ | ​ | 203,513
Total fair value of debt | ​ | $ | — | ​ | $ | 445,849 | ​ | $ | — | ​ | $ | 445,849
(1) | The investments, which consisted of equity investments of $130.5 million and money market funds of $174.2 million, held by ISP Fund LP were subject to a 36-month lock-up period from our initial contribution date, December 11, 2020.
​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Estimated Fair Value Measurements as of December 31, 2020 Using:
​ | ​ | Quoted Price | ​ | Significant | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | in Active | ​ | Other | ​ | Significant | ​ | ​ | ​
​ | ​ | Markets for | ​ | Observable | ​ | Unobservable | ​ | ​ | ​
Types of Instruments | ​ | Identical Assets | ​ | Inputs | ​ | Inputs | ​ | ​ | ​
(In thousands) |  | Level 1 |  | Level 2 |  | Level 3 |  | Total
Assets | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Money market funds | ​ | $ | 204,808 | ​ | $ | — | ​ | $ | — | ​ | $ | 204,808
Investments held by ISP Fund LP (1) | ​ | ​ | 299,288 | ​ | ​ | — | ​ | ​ | — | ​ | ​ | 299,288
Equity investment - Armata Common Stock | ​ | ​ | 25,958 | ​ |  | — | ​ |  | — | ​ |  | 25,958
Equity investment - Armata Warrants | ​ | ​ | — | ​ |  | 18,049 | ​ |  | — | ​ |  | 18,049
Equity investment - Entasis Common Stock | ​ | ​ | 46,122 | ​ |  | — | ​ |  | — | ​ |  | 46,122
Equity investment - Entasis Warrants | ​ | ​ | — | ​ |  | 31,882 | ​ |  | — | ​ |  | 31,882
Equity investment - InCarda Warrants | ​ | ​ | — | ​ | ​ | — | ​ | ​ | 1,147 | ​ | ​ | 1,147
Total assets measured at estimated fair value | ​ | $ | 576,176 | ​ | $ | 49,931 | ​ | $ | 1,147 | ​ | $ | 627,254
Debt | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
2023 Notes | ​ | $ | — | ​ | $ | 239,779 | ​ | $ | — | ​ | $ | 239,779
2025 Notes | ​ | ​ | — | ​ | ​ | 206,135 | ​ | ​ | — | ​ | ​ | 206,135
Total fair value of debt | ​ | $ | — | ​ | $ | 445,914 | ​ | $ | — | ​ | $ | 445,914
(1) | The investments, which consisted of equity investments of $14.5 million and money market funds of $284.8 million, held by ISP Fund LP were subject to a 36-month lock-up period from our initial contribution date, December 11, 2020.

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- Definition Tabular disclosure of financial instruments measured at fair value, including those classified in shareholders' equity measured on a recurring or nonrecurring basis. Disclosures include, but are not limited to, fair value measurements recorded and the reasons for the measurements, level within the fair value hierarchy in which the fair value measurements are categorized and transfers between levels 1 and 2. Nonrecurring fair value measurements are those that are required or permitted in the statement of financial position in particular circumstances. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=117815213&loc=d3e19207-110258 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 3 -URI http://asc.fasb.org/extlink&oid=117815213&loc=d3e19279-110258 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2C -URI http://asc.fasb.org/extlink&oid=117815213&loc=SL7498348-110258 Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=117815213&loc=d3e19207-110258 Reference 5: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (bb) -URI http://asc.fasb.org/extlink&oid=117815213&loc=d3e19207-110258 + Details
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