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CONSOLIDATED ENTITIES - Pulmoquine Therapeutics, Inc. (Details) - USD ($) $ in Thousands | 1 Months Ended | 12 Months Ended
--- | --- | ---
Sep. 30, 2021 | Apr. 30, 2020 | Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019
CONSOLIDATED ENTITIES |  |  |  |  |
Total assets |  |  | $ 926,395 | $ 999,570 |
Cash balance |  |  | 201,525 | 246,487 |
Total operating expenses |  |  | 16,763 | 15,671 | $ 14,656
Pulmoquine Therapeutics, Inc. |  |  |  |  |
CONSOLIDATED ENTITIES |  |  |  |  |
Proceeds from net distribution on dissolution of Pulmoquine | $ 2,400 |  |  |  |
Total assets |  |  | 0 | 3,500 |
Net loss |  |  | 500 | 2,200 |
Total operating expenses |  |  | $ 700 | $ 2,000 |
Pulmoquine Therapeutics, Inc. | Series A preferred stock |  |  |  |  |
CONSOLIDATED ENTITIES |  |  |  |  |
Securities to be purchased |  | 5,808,550 |  |  |
Securities Purchase Agreement, Amount |  | $ 5,000 |  |  |

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