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FINANCIAL INSTRUMENTS AND FAIR VALUE MEASUREMENTS - Convertible Promissory Note in Gate Neurosciences (Details) - USD ($) $ in Thousands |  | 12 Months Ended |
--- | --- | --- | ---
Nov. 24, 2021 | Dec. 31, 2021 | Dec. 31, 2020
Debt Instrument [Line Items] |  |  |
Number of common stock issued description | The number of common stock shares to be issued in a qualified event shall be equal to the amount due on the conversion date divided by the lesser of a capped conversion price (the "Capped Conversion Price") and the qualified event price (the "Qualified Event Price"). The Capped Conversion Price is calculated as $50.0 million divided by the number of common stock outstanding at such time on a fully diluted basis. The Qualified Event Price is the price per share determined by the qualified event. A qualified financing is a sale or series of sales of preferred stock where (i) at least 50 percent of counterparties are not existing shareholders, (ii) net proceeds to Gate are at least $35.0 million, and (iii) the stated or implied equity valuation of Gate is at least $80.0 million. Shadow Preferred means preferred stock having identical rights, preferences and restrictions as the preferred stock that would be issued in a qualified financing. |  |
Long-term Investments |  | $ 483,845 | $ 438,258
Gate Neuroscience [Member] |  |  |
Debt Instrument [Line Items] |  |  |
Debt Instrument Transaction Cost |  | 900 |
Unrealized loss from fair value changes in equity investments |  | 800 |
Long-term Investments |  | $ 15,900 |
Gate Neuroscience [Member] | Common Stock [Member] |  |  |
Debt Instrument [Line Items] |  |  |
Debt Instrument, Interest Rate, Effective Percentage | 8.00% |  |
Convertible Promissory Note Purchase Agreement [Member] | Gate Neuroscience [Member] |  |  |
Debt Instrument [Line Items] |  |  |
Debt Instrument, Principal Payment | $ 15,000 |  |

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