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REVENUE RECOGNITION AND COLLABORATIVE ARRANGEMENTS (Details) - USD ($) $ in Thousands | 12 Months Ended |
--- | --- | ---
Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2014
Revenue Recognition and Collaborative Arrangements |  |  |  |
Total net revenue | $ 391,866 | $ 336,794 | $ 261,016 |
Strategic alliance - MABA program |  |  |  |
Revenue Recognition and Collaborative Arrangements |  |  |  |
Revenue recognized upon termination of contract |  | 10,000 |  |
Royalty revenue from a related party |  |  |  |
Revenue Recognition and Collaborative Arrangements |  |  |  |
Total net revenue | 391,866 | 326,794 | 261,016 |
Revenue from collaborative arrangements |  |  |  |
Revenue Recognition and Collaborative Arrangements |  |  |  |
Total net revenue | 0 | 10,000 | 0 |
GSK |  |  |  |
Revenue Recognition and Collaborative Arrangements |  |  |  |
Total net revenue | 391,866 | 336,794 | 261,016 |
Milestone fees paid | $ 220,000 | 220,000 |  |
GSK | Long-Acting Beta2 Agonist (LABA) Collaboration |  |  |  |
Revenue Recognition and Collaborative Arrangements |  |  |  |
Milestone fees paid |  |  |  | $ 220,000
Percentage of economic interest in any future payments made under the agreements | 15.00% |  |  |
GSK | Royalty revenue from a related party |  |  |  |
Revenue Recognition and Collaborative Arrangements |  |  |  |
Gross Revenue from Contract with Customer, Excluding Assessed Tax, Before Amortization Of Capitalized Fees | $ 405,689 | 340,617 | 274,839 |
Less: amortization of capitalized fees paid to a related party | (13,823) | (13,823) | (13,823) |
Total net revenue | 391,866 | 326,794 | 261,016 |
GSK | RELVAR/BREO |  |  |  |
Revenue Recognition and Collaborative Arrangements |  |  |  |
Gross Revenue from Contract with Customer, Excluding Assessed Tax, Before Amortization Of Capitalized Fees | $ 234,066 | 221,536 | 189,424 |
GSK | RELVAR/BREO | Long-Acting Beta2 Agonist (LABA) Collaboration |  |  |  |
Revenue Recognition and Collaborative Arrangements |  |  |  |
Royalty rate for first level of annual global net sales (as a percent) | 15.00% |  |  |
Annual global sales level used to determine royalty rate | $ 3,000,000 |  |  |
Royalty rate for sales above first level of annual global net sales (as a percent) | 5.00% |  |  |
GSK | ANORO |  |  |  |
Revenue Recognition and Collaborative Arrangements |  |  |  |
Gross Revenue from Contract with Customer, Excluding Assessed Tax, Before Amortization Of Capitalized Fees | $ 44,935 | 45,992 | 42,625 |
GSK | ANORO | Long-Acting Beta2 Agonist (LABA) Collaboration | Minimum |  |  |  |
Revenue Recognition and Collaborative Arrangements |  |  |  |
Royalty rate for combination products (as a percent) | 6.50% |  |  |
GSK | ANORO | Long-Acting Beta2 Agonist (LABA) Collaboration | Maximum |  |  |  |
Revenue Recognition and Collaborative Arrangements |  |  |  |
Royalty rate for combination products (as a percent) | 10.00% |  |  |
GSK | TRELEGY |  |  |  |
Revenue Recognition and Collaborative Arrangements |  |  |  |
Gross Revenue from Contract with Customer, Excluding Assessed Tax, Before Amortization Of Capitalized Fees | $ 126,688 | 73,089 | 42,790 |
GSK | TRELEGY | Long-Acting Beta2 Agonist (LABA) Collaboration | Minimum |  |  |  |
Revenue Recognition and Collaborative Arrangements |  |  |  |
Royalty rate for combination products (as a percent) | 6.50% |  |  |
GSK | TRELEGY | Long-Acting Beta2 Agonist (LABA) Collaboration | Maximum |  |  |  |
Revenue Recognition and Collaborative Arrangements |  |  |  |
Royalty rate for combination products (as a percent) | 10.00% |  |  |
GSK | Revenue from collaborative arrangements | Strategic alliance - MABA program |  |  |  |
Revenue Recognition and Collaborative Arrangements |  |  |  |
strategic alliance - MABA program | $ 0 | $ 10,000 | $ 0 |

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