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EQUITY AND LONG-TERM INVESTMENTS AND FAIR VALUE MEASUREMENTS - Schedule of Available-for-Sale Securities Measured at Fair Value on a Recurring Basis (Details) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2022 | Dec. 31, 2021
Fair Value Measurements |  |  |  |  |
Contingent value rights liability |  | $ 595 |  |  |
ISP Fund LP |  |  |  |  |
Liabilities |  |  |  |  |
Lock-up period |  | 36 months |  | 36 months |
Contributed to partnership for investing |  | $ 300,000 |  |  |
Money market funds | ISP Fund LP |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  | 25,100 |  | $ 3,500 |
Equity investment | ISP Fund LP |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  | 295,400 |  | 192,200 |
Private Placement Positions And Convertible Notes | ISP Fund LP |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  | 54,600 |  |  |
Recurring basis |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  | 639,488 |  | 606,792 |
Recurring basis | Money market funds |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  | 263,469 |  | 145,132 |
Recurring basis | Equity investments and Money market funds | ISP Fund LP |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  | 320,560 | [1] | 195,745 | [2]
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  | 560,546 |  | 489,704 |
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | ISP Fund LP |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value | [1] | 265,982 |  |  |
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Money market funds |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  | 263,469 |  | 145,132 |
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investments and Money market funds | ISP Fund LP |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value | [2] |  |  | 193,677 |
Recurring basis | Significant Other Observable Inputs, Level 2 |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  | 8,059 |  | 99,509 |
Recurring basis | Significant Unobservable Inputs, Level 3 |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  | 70,883 |  | 17,579 |
Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investments and Money market funds | ISP Fund LP |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  | 54,578 | [1] | 2,068 | [2]
Nonrecurring basis |  |  |  |  |
Fair Value Measurements |  |  |  |  |
Contingent value rights liability |  | 595 |  |  |
Liabilities |  |  |  |  |
Total liabilities at estimated fair value |  | 506,259 |  |  |
Nonrecurring basis | Debt |  |  |  |  |
Fair Value Measurements |  |  |  |  |
2023 Notes |  | 96,089 |  | 261,769 |
2025 Notes |  | 197,807 |  | 234,498 |
2028 Notes |  | 211,768 |  |  |
Total fair value of debt |  | 505,664 |  | 496,267 |
Nonrecurring basis | Significant Other Observable Inputs, Level 2 |  |  |  |  |
Fair Value Measurements |  |  |  |  |
2028 Notes |  | 211,768 |  |  |
Total fair value of debt |  | 505,664 |  |  |
Liabilities |  |  |  |  |
Total liabilities at estimated fair value |  | 505,664 |  |  |
Nonrecurring basis | Significant Other Observable Inputs, Level 2 | Debt |  |  |  |  |
Fair Value Measurements |  |  |  |  |
2023 Notes |  | 96,089 |  | 261,769 |
2025 Notes |  | 197,807 |  | 234,498 |
Total fair value of debt |  |  |  | 496,267 |
Nonrecurring basis | Significant Unobservable Inputs, Level 3 |  |  |  |  |
Fair Value Measurements |  |  |  |  |
Contingent value rights liability |  | 595 |  |  |
Liabilities |  |  |  |  |
Total liabilities at estimated fair value |  | 595 |  |  |
Armata | Recurring basis | Equity investment | Common stock |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  | 31,095 |  | 88,101 |
Armata | Recurring basis | Equity investment | Warrants |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  | 8,059 |  | 58,595 |
Armata | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investment | Common stock |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  | 31,095 |  | 88,101 |
Armata | Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investment | Warrants |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  | 8,059 |  | 58,595 |
Entasis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investment | Common stock |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  |  |  | 62,794 |
Entasis | Recurring basis | Equity investment | Common stock |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  |  |  | 62,794 |
Entasis | Recurring basis | Equity investment | Warrants |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  |  |  | 40,914 |
Entasis | Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investment | Warrants |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  |  |  | 40,914 |
InCarda | Recurring basis | Equity investment | Warrants |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  | 605 |  | 411 |
InCarda | Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investment | Warrants |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  | 605 |  | 411 |
Gate Neurosciences Member | Recurring basis | Convertible debt investment |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  | 15,700 |  | 15,100 |
Gate Neurosciences Member | Recurring basis | Significant Unobservable Inputs, Level 3 | Convertible debt investment |  |  |  |  |
Assets |  |  |  |  |
Total assets measured at estimated fair value |  | $ 15,700 |  | $ 15,100 |
[1] | The investments held by ISP Fund LP, consisted of $295.4 million in equity investments, which included private placement positions and convertible notes of $54.6 million, and $25.1 million in money market funds. Our total capital contribution of $300.0 million is subject to a 36-month lock-up period from the date of such capital contributions.
[2] | The investments held by ISP Fund LP, consisted of $192.2 million equity investments and $3.5 million money market funds, are subject to a 36-month lock-up period from our initial contribution date, December 11, 2020.

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