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Net Income Per Share - Basic and Diluted EPS (Details) - USD ($)
$ / shares in Units, shares in Thousands, $ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Numerator:      
Net income attributable to Innoviva stockholders, basic $ 23,392 $ 179,722 $ 213,921
Net income attributable to Innoviva stockholders, diluted $ 26,860 $ 191,304 $ 225,569
Denominator:      
Weighted-average shares used to compute basic net income per share attributable to Innoviva stockholders 62,726 65,435 69,644
Dilutive effect of options and awards granted under equity incentive plan and employee stock purchase plan 311 149 108
Weighted-average shares used to compute diluted net income per share attributable to Innoviva stockholders 74,187 86,876 95,248
Net income per share attributable to Innoviva stockholders      
Basic net income per share $ 0.37 $ 2.75 $ 3.07
Diluted net income per share $ 0.36 $ 2.2 $ 2.37
2023 Notes      
Numerator:      
Add: interest expense on Notes, net of tax effect $ 0 $ 89 $ 2,439
Denominator:      
Dilutive effect 0 187 6,188
2025 Notes      
Numerator:      
Add: interest expense on Notes, net of tax effect $ 3,468 $ 5,116 $ 4,583
Denominator:      
Dilutive effect 11,150 11,150 11,150
2028 Notes      
Numerator:      
Add: interest expense on Notes, net of tax effect $ 0 $ 6,377 $ 4,626
Denominator:      
Dilutive effect 0 9,955 8,158