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Equity and Long-term Investments and Fair Value Measurements - Convertible Promissory Note in Gate Neurosciences (Details) - USD ($)
$ in Thousands
 12 Months Ended
Nov. 13, 2024
Aug. 05, 2024
Feb. 13, 2024
Oct. 06, 2023
Feb. 02, 2023
Nov. 24, 2021
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Equity Investment                  
Additional cash investment             $ 0 $ 1,218 $ 13,725
Gate Neuroscience [Member]                  
Equity Investment                  
Number of common stock issued description           The number of common stock shares to be issued in a qualified event shall be equal to the amount due on the conversion date divided by the lesser of a capped conversion price (the “Capped Conversion Price”) and the qualified event price (the “Qualified Event Price”). The Capped Conversion Price is calculated as $50.0 million divided by the number of shares of common stock outstanding at such time on a fully diluted basis. The Qualified Event Price is the price per share determined by the qualified event. A qualified financing is a sale or series of sales of preferred stock where (i) at least 50 percent of counterparties are not existing shareholders, (ii) net proceeds to Gate are at least $35.0 million, and (iii) the stated or implied equity valuation of Gate is at least $80.0 million.      
Equity and long-term investments at fair value             $ 50,900 28,000  
Unrealized gain from fair value changes in equity investments                 $ 600
Unrealized loss from fair value changes in equity investments               $ 400  
Convertible Promissory Note Purchase Agreement | Gate Neuroscience [Member]                  
Equity Investment                  
Debt Instrument, Interest Rate, Effective Percentage           8.00%      
Convertible notes face value   $ 39,800 $ 33,500 $ 27,700 $ 21,500 $ 15,000      
Convertible Promissory Note Purchase Agreement Amendment | Gate Neuroscience [Member]                  
Equity Investment                  
Convertible notes face value         21,500        
Additional cash investment         $ 5,000        
Convertible Promissory Note Purchase Agreement Second Amendment | Gate Neuroscience [Member]                  
Equity Investment                  
Convertible notes face value       27,700          
Additional cash investment       $ 5,000          
Convertible Promissory Note Purchase Agreement Third Amendment | Gate Neuroscience [Member]                  
Equity Investment                  
Convertible notes face value     33,500            
Additional cash investment     $ 5,000            
Convertible Promissory Note Purchase Agreement Fourth Amendment | Gate Neuroscience [Member]                  
Equity Investment                  
Convertible notes face value   39,800              
Additional cash investment   $ 5,000              
Convertible Promissory Note Purchase Agreement Fifth Amendment | Gate Neuroscience [Member]                  
Equity Investment                  
Convertible notes face value $ 50,600                
Additional cash investment $ 10,000