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Equity and Long-term Investments and Fair Value Measurements - Schedule of Available-for-Sale Securities Measured at Fair Value on a Recurring Basis (Details) - USD ($)
$ in Thousands
Dec. 31, 2024
Dec. 31, 2023
Fair Value Measurements    
Contingent value rights $ 0 $ 359
Recurring basis    
Assets    
Total assets measured at estimated fair value 765,285 705,963
Recurring basis | Money market funds    
Assets    
Total assets measured at estimated fair value 289,441 170,706
Recurring basis | Equity investments and Money market funds | ISP Fund LP    
Assets    
Total assets measured at estimated fair value 255,658 311,812
Recurring basis | Term loan investment | Armata July 2023 Term Loan    
Assets    
Total assets measured at estimated fair value 30,197 27,044
Recurring basis | Term loan investment | Armata March 2024 Term Loan    
Assets    
Total assets measured at estimated fair value 39,275  
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1    
Assets    
Total assets measured at estimated fair value 529,393 503,162
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Money market funds    
Assets    
Total assets measured at estimated fair value 289,441 170,706
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investments and Money market funds | ISP Fund LP    
Assets    
Total assets measured at estimated fair value 193,560 251,207
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Term loan investment | Armata July 2023 Term Loan    
Assets    
Total assets measured at estimated fair value 0 0
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Term loan investment | Armata March 2024 Term Loan    
Assets    
Total assets measured at estimated fair value 0  
Recurring basis | Significant Other Observable Inputs, Level 2    
Assets    
Total assets measured at estimated fair value 5,901 35,297
Recurring basis | Significant Other Observable Inputs, Level 2 | Money market funds    
Assets    
Total assets measured at estimated fair value 0 0
Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investments and Money market funds | ISP Fund LP    
Assets    
Total assets measured at estimated fair value 0 0
Recurring basis | Significant Other Observable Inputs, Level 2 | Term loan investment | Armata July 2023 Term Loan    
Assets    
Total assets measured at estimated fair value 0 0
Recurring basis | Significant Other Observable Inputs, Level 2 | Term loan investment | Armata March 2024 Term Loan    
Assets    
Total assets measured at estimated fair value 0  
Recurring basis | Significant Unobservable Inputs, Level 3    
Assets    
Total assets measured at estimated fair value 229,991 167,504
Recurring basis | Significant Unobservable Inputs, Level 3 | Money market funds    
Assets    
Total assets measured at estimated fair value 0 0
Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investments and Money market funds | ISP Fund LP    
Assets    
Total assets measured at estimated fair value 62,098 60,605
Recurring basis | Significant Unobservable Inputs, Level 3 | Term loan investment | Armata July 2023 Term Loan    
Assets    
Total assets measured at estimated fair value 30,197 27,044
Recurring basis | Significant Unobservable Inputs, Level 3 | Term loan investment | Armata March 2024 Term Loan    
Assets    
Total assets measured at estimated fair value 39,275  
Nonrecurring basis    
Fair Value Measurements    
Contingent value rights   359
Liabilities    
Total liabilities at estimated fair value   427,836
Nonrecurring basis | Debt    
Fair Value Measurements    
Total fair value of debt 473,566 427,477
Nonrecurring basis | Quoted Price in Active Markets for Identical Assets, Level 1    
Fair Value Measurements    
Contingent value rights   0
Liabilities    
Total liabilities at estimated fair value   0
Nonrecurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Debt    
Fair Value Measurements    
Total fair value of debt 0 0
Nonrecurring basis | Significant Other Observable Inputs, Level 2    
Fair Value Measurements    
Contingent value rights   0
Liabilities    
Total liabilities at estimated fair value   427,477
Nonrecurring basis | Significant Other Observable Inputs, Level 2 | Debt    
Fair Value Measurements    
Total fair value of debt 473,566 427,477
Nonrecurring basis | Significant Unobservable Inputs, Level 3    
Fair Value Measurements    
Contingent value rights   359
Liabilities    
Total liabilities at estimated fair value   359
Nonrecurring basis | Significant Unobservable Inputs, Level 3 | Debt    
Fair Value Measurements    
Total fair value of debt 0 0
Nonrecurring basis | 2025 Notes | Debt    
Fair Value Measurements    
2025 Notes 222,353 200,407
Nonrecurring basis | 2025 Notes | Quoted Price in Active Markets for Identical Assets, Level 1 | Debt    
Fair Value Measurements    
2025 Notes 0 0
Nonrecurring basis | 2025 Notes | Significant Other Observable Inputs, Level 2 | Debt    
Fair Value Measurements    
2025 Notes 222,353 200,407
Nonrecurring basis | 2025 Notes | Significant Unobservable Inputs, Level 3 | Debt    
Fair Value Measurements    
2025 Notes 0 0
Nonrecurring basis | 2028 Notes | Debt    
Fair Value Measurements    
2028 Notes 251,213 227,070
Nonrecurring basis | 2028 Notes | Quoted Price in Active Markets for Identical Assets, Level 1 | Debt    
Fair Value Measurements    
2028 Notes 0 0
Nonrecurring basis | 2028 Notes | Significant Other Observable Inputs, Level 2 | Debt    
Fair Value Measurements    
2028 Notes 251,213 227,070
Nonrecurring basis | 2028 Notes | Significant Unobservable Inputs, Level 3 | Debt    
Fair Value Measurements    
2028 Notes 0 0
Armata | Recurring basis | Convertible debt investment    
Assets    
Total assets measured at estimated fair value 42,095 51,883
Armata | Recurring basis | Equity investment | Common stock    
Assets    
Total assets measured at estimated fair value 46,392 81,249
Armata | Recurring basis | Equity investment | Warrants    
Assets    
Total assets measured at estimated fair value 5,901 35,297
Armata | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Convertible debt investment    
Assets    
Total assets measured at estimated fair value 0 0
Armata | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investment | Common stock    
Assets    
Total assets measured at estimated fair value 46,392 81,249
Armata | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investment | Warrants    
Assets    
Total assets measured at estimated fair value 0 0
Armata | Recurring basis | Significant Other Observable Inputs, Level 2 | Convertible debt investment    
Assets    
Total assets measured at estimated fair value 0 0
Armata | Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investment | Common stock    
Assets    
Total assets measured at estimated fair value 0 0
Armata | Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investment | Warrants    
Assets    
Total assets measured at estimated fair value 5,901 35,297
Armata | Recurring basis | Significant Unobservable Inputs, Level 3 | Convertible debt investment    
Assets    
Total assets measured at estimated fair value 42,095 51,883
Armata | Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investment | Common stock    
Assets    
Total assets measured at estimated fair value 0 0
Armata | Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investment | Warrants    
Assets    
Total assets measured at estimated fair value 0 0
InCarda | Recurring basis | Convertible debt investment    
Assets    
Total assets measured at estimated fair value 436  
InCarda | Recurring basis | Equity investment | Warrants    
Assets    
Total assets measured at estimated fair value 59  
InCarda | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Convertible debt investment    
Assets    
Total assets measured at estimated fair value 0  
InCarda | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investment | Warrants    
Assets    
Total assets measured at estimated fair value 0  
InCarda | Recurring basis | Significant Other Observable Inputs, Level 2 | Convertible debt investment    
Assets    
Total assets measured at estimated fair value 0  
InCarda | Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investment | Warrants    
Assets    
Total assets measured at estimated fair value 0  
InCarda | Recurring basis | Significant Unobservable Inputs, Level 3 | Convertible debt investment    
Assets    
Total assets measured at estimated fair value 436  
InCarda | Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investment | Warrants    
Assets    
Total assets measured at estimated fair value 59  
ImaginAb | Recurring basis | Convertible debt investment    
Assets    
Total assets measured at estimated fair value 4,950  
ImaginAb | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Convertible debt investment    
Assets    
Total assets measured at estimated fair value 0  
ImaginAb | Recurring basis | Significant Other Observable Inputs, Level 2 | Convertible debt investment    
Assets    
Total assets measured at estimated fair value 0  
ImaginAb | Recurring basis | Significant Unobservable Inputs, Level 3 | Convertible debt investment    
Assets    
Total assets measured at estimated fair value 4,950  
Gate Neuroscience [Member] | Recurring basis | Convertible debt investment    
Assets    
Total assets measured at estimated fair value 50,881 27,972
Gate Neuroscience [Member] | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Convertible debt investment    
Assets    
Total assets measured at estimated fair value 0 0
Gate Neuroscience [Member] | Recurring basis | Significant Other Observable Inputs, Level 2 | Convertible debt investment    
Assets    
Total assets measured at estimated fair value 0 0
Gate Neuroscience [Member] | Recurring basis | Significant Unobservable Inputs, Level 3 | Convertible debt investment    
Assets    
Total assets measured at estimated fair value $ 50,881 $ 27,972