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Debt - Convertible Subordinated Notes (Details)
1 Months Ended 3 Months Ended 12 Months Ended
Apr. 18, 2022
USD ($)
Mar. 07, 2022
USD ($)
Jul. 31, 2014
$ / shares
Jan. 31, 2013
USD ($)
Item
$ / shares
shares
Mar. 31, 2022
USD ($)
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Dec. 31, 2016
USD ($)
Debt                  
Payment for repurchase of debt instrument           $ 0 $ 96,204,000 $ 165,131,000  
Accrued interest payable           3,422,000 3,422,000    
Loss on extinguishment of debt           0 0 (20,662,000)  
Debt discount and issuance costs, net           $ 5,156,000 7,266,000    
2023 Notes | Convertible subordinated notes                  
Debt                  
Loan amount       $ 287,500,000          
Debt Instrument, annual interest rate       2.125%          
Portion of debt retired, face value   $ 144,800,000     $ 144,800,000       $ 14,100,000
Portion of debt retired, carrying value   144,500,000             $ 13,900,000
Payment for repurchase of debt instrument   $ 165,600,000     $ 165,600,000        
Percentage of notes repurchased   60.00%              
Accrued interest payable   $ 400,000              
Unamortized debt issuance cost   300,000              
Loss on extinguishment of debt   (20,700,000)              
Principal $ 96,200,000 96,200,000              
Debt discount and issuance costs, net   $ 200,000              
Interest expense                  
Contractual interest expense             85,000 2,617,000  
Amortization of debt issuance costs             11,000 302,000  
Total interest and amortization expense             $ 96,000 $ 2,919,000  
2023 Notes | Convertible subordinated notes | Privately-negotiated capped call option                  
Debt                  
Number of derivative instruments purchased | Item       2          
Strike price for the underlying number of shares (in dollars per share) | $ / shares     $ 19.77 $ 27.79          
2023 Notes | Convertible subordinated notes | Stock prices below $27.79 per share | Minimum                  
Debt                  
Net shares settlement payable to the entity | shares       0          
2023 Notes | Convertible subordinated notes | Stock prices below $27.79 per share | Maximum                  
Debt                  
Net shares settlement payable to the entity | shares       2,779,659          
2023 Notes | Convertible subordinated notes | Privately-negotiated cap price                  
Debt                  
Strike price for the underlying number of shares (in dollars per share) | $ / shares     $ 27.04 $ 38          
2023 Notes | Old Rate [Member] | Convertible subordinated notes                  
Debt                  
Effective interest rate   2.36%              
2023 Notes | New Rate [Member] | Convertible subordinated notes                  
Debt                  
Effective interest rate   2.37%              
Innoviva's Common Stock | 2023 Notes | Convertible subordinated notes                  
Debt                  
Notes converted into common stock, Amount $ 3,000                
Common stock | 2023 Notes | Convertible subordinated notes                  
Debt                  
Conversion rate for shares of common stock per $1,000 principal     50.5818 35.9903          
Conversion price (dollars per share) | $ / shares     $ 19.77 $ 27.79