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Description of Operations and Summary of Significant Accounting Policies (Details) $ in Billions | 3 Months Ended | 6 Months Ended | 12 Months Ended
--- | --- | --- | ---
Jun. 30, 2025 | Jun. 30, 2024 Customer | Jun. 30, 2025 USD ($) Customer | Jun. 30, 2024 | Dec. 31, 2024
Net product sales |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |
Number of major customers | Customer |  | 3 | 3 |  |
Net product sales | Net Product Sales | Customer One |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |
Concentration Risk, Percentage | 26.00% |  | 27.00% |  |
Net product sales | Net Product Sales | Customer Two |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |
Concentration Risk, Percentage | 26.00% |  | 26.00% |  |
Net product sales | Net Product Sales | Customer Three |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |
Concentration Risk, Percentage | 24.00% |  | 25.00% |  |
Net product sales | Receivables from Net Product Sales | Customer One |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |
Concentration Risk, Percentage |  |  | 33.00% |  |
Net product sales | Receivables from Net Product Sales | Customer Two |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |
Concentration Risk, Percentage |  |  | 14.00% |  |
Net product sales | Receivables from Net Product Sales | Customer Three |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |
Concentration Risk, Percentage |  |  | 14.00% |  |
Net product sales | Customer Concentration Risk | Net Product Sales | Customer One |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |
Concentration Risk, Percentage |  | 32.00% |  | 34.00% |
Net product sales | Customer Concentration Risk | Net Product Sales | Customer Two |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |
Concentration Risk, Percentage |  | 23.00% |  | 24.00% |
Net product sales | Customer Concentration Risk | Net Product Sales | Customer Three |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |
Concentration Risk, Percentage |  | 27.00% |  | 25.00% |
Net product sales | Customer Concentration Risk | Receivables from Net Product Sales | Customer One |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |
Concentration Risk, Percentage |  |  |  |  | 31.00%
Net product sales | Customer Concentration Risk | Receivables from Net Product Sales | Customer Two |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |
Concentration Risk, Percentage |  |  |  |  | 18.00%
Net product sales | Customer Concentration Risk | Receivables from Net Product Sales | Customer Three |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |
Concentration Risk, Percentage |  |  |  |  | 15.00%
Long-Acting Beta2 Agonist (LABA) Collaboration | GSK | RELVAR/BREO |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |
Royalty rate for first level of annual global net sales (as a percent) |  |  | 15.00% |  |
Annual global sales level used to determine royalty rate | $ |  |  | $ 3.0 |  |
Royalty rate for sales above first level of annual global net sales (as a percent) |  |  | 5.00% |  |
Long-Acting Beta2 Agonist (LABA) Collaboration | GSK | ANORO | Minimum |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |
Royalty rate for combination products (as a percent) |  |  | 6.50% |  |
Long-Acting Beta2 Agonist (LABA) Collaboration | GSK | ANORO | Maximum |  |  |  |  |
Description of Operations and Summary of Significant Accounting Policies |  |  |  |  |
Royalty rate for combination products (as a percent) |  |  | 10.00% |  |

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