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Description of Operations and Summary of Significant Accounting Policies (Details) $ in Billions	3 Months Ended		6 Months Ended		12 Months Ended
	Jun. 30, 2025	Jun. 30, 2024 Customer	Jun. 30, 2025 USD ($) Customer	Jun. 30, 2024	Dec. 31, 2024
Net product sales
Description of Operations and Summary of Significant Accounting Policies
Number of major customers | Customer		3	3
Net product sales | Net Product Sales | Customer One
Description of Operations and Summary of Significant Accounting Policies
Concentration Risk, Percentage	26.00%		27.00%
Net product sales | Net Product Sales | Customer Two
Description of Operations and Summary of Significant Accounting Policies
Concentration Risk, Percentage	26.00%		26.00%
Net product sales | Net Product Sales | Customer Three
Description of Operations and Summary of Significant Accounting Policies
Concentration Risk, Percentage	24.00%		25.00%
Net product sales | Receivables from Net Product Sales | Customer One
Description of Operations and Summary of Significant Accounting Policies
Concentration Risk, Percentage			33.00%
Net product sales | Receivables from Net Product Sales | Customer Two
Description of Operations and Summary of Significant Accounting Policies
Concentration Risk, Percentage			14.00%
Net product sales | Receivables from Net Product Sales | Customer Three
Description of Operations and Summary of Significant Accounting Policies
Concentration Risk, Percentage			14.00%
Net product sales | Customer Concentration Risk | Net Product Sales | Customer One
Description of Operations and Summary of Significant Accounting Policies
Concentration Risk, Percentage		32.00%		34.00%
Net product sales | Customer Concentration Risk | Net Product Sales | Customer Two
Description of Operations and Summary of Significant Accounting Policies
Concentration Risk, Percentage		23.00%		24.00%
Net product sales | Customer Concentration Risk | Net Product Sales | Customer Three
Description of Operations and Summary of Significant Accounting Policies
Concentration Risk, Percentage		27.00%		25.00%
Net product sales | Customer Concentration Risk | Receivables from Net Product Sales | Customer One
Description of Operations and Summary of Significant Accounting Policies
Concentration Risk, Percentage					31.00%
Net product sales | Customer Concentration Risk | Receivables from Net Product Sales | Customer Two
Description of Operations and Summary of Significant Accounting Policies
Concentration Risk, Percentage					18.00%
Net product sales | Customer Concentration Risk | Receivables from Net Product Sales | Customer Three
Description of Operations and Summary of Significant Accounting Policies
Concentration Risk, Percentage					15.00%
Long-Acting Beta2 Agonist (LABA) Collaboration | GSK | RELVAR/BREO
Description of Operations and Summary of Significant Accounting Policies
Royalty rate for first level of annual global net sales (as a percent)			15.00%
Annual global sales level used to determine royalty rate | $			$ 3.0
Royalty rate for sales above first level of annual global net sales (as a percent)			5.00%
Long-Acting Beta2 Agonist (LABA) Collaboration | GSK | ANORO | Minimum
Description of Operations and Summary of Significant Accounting Policies
Royalty rate for combination products (as a percent)			6.50%
Long-Acting Beta2 Agonist (LABA) Collaboration | GSK | ANORO | Maximum
Description of Operations and Summary of Significant Accounting Policies
Royalty rate for combination products (as a percent)			10.00%

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For an entity that discloses a concentration risk in relation to quantitative amount, which serves as the "benchmark" (or denominator) in the equation, this concept represents the concentration percentage derived from the division.

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Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 280
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Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef
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Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef
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Reference 5: http://www.xbrl.org/2009/role/commonPracticeRef
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Reference 6: http://www.xbrl.org/2009/role/commonPracticeRef
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