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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2025
Mar. 31, 2025
Jun. 30, 2024
Mar. 31, 2024
Jun. 30, 2025
Jun. 30, 2024
Dec. 31, 2024
Cash flows from operating activities              
Net income $ 63,688 $ (46,584) $ (34,685) $ 36,532 $ 17,104 $ 1,847  
Adjustments to reconcile net income to net cash provided by operating activities:              
Deferred income taxes         (877) (12,009)  
Amortization of capitalized fees and depreciation of property and equipment         6,976 6,986  
Amortization of acquired intangible assets 6,500   6,400   13,022 12,880  
Inventory fair value step-up adjustment included in cost of products sold         625 10,306  
Stock-based compensation         4,569 3,098  
Amortization of debt discount and issuance costs         1,078 1,048  
Changes in fair values of equity method investments, net (13,082)   60,108   467 24,766  
Changes in fair values of equity and long-term investments, net 11,280   (30,556)   (54,019) (43,891) $ (59,161)
Other non-cash items         423 (153)  
Changes in operating assets and liabilities:              
Accounts receivable         (533) (12,328)  
Receivables from collaboration arrangement         (1,362) 2,423  
Inventory         (17,146) (6,233)  
Prepaid expenses         4,453 13,146  
Other assets         774 1,604  
Accounts payable         3,250 (4,678)  
Accrued personnel-related expenses and other accrued liabilities         1,932 (5,950)  
Accrued interest payable         (4) 0  
Income tax payable         1,921 543  
Deferred revenue         1,999 (422)  
Net cash provided by operating activities         92,690 80,765  
Cash flows from investing activities              
Purchases of trading securities         (34,674) (43,136)  
Proceeds from trading securities         5,097 0  
Purchases of equity investments managed by ISP Fund LP         0 (30,892)  
Sales of equity investments managed by ISP Fund LP         19,939 5,976  
Purchases and sales of other investments managed by ISP Fund LP, net         8,086 24,916  
Sale of property and equipment         0 98  
Net cash used in investing activities         (1,552) (43,038)  
Cash flows from financing activities              
Repurchase of common stock         0 (14,777)  
Repurchase of shares to satisfy tax withholding         (91) (105)  
Proceeds from issuances of common stock, net         1,521 645  
Net cash provided by (used in) financing activities         1,430 (14,237)  
Net increase in cash and cash equivalents         92,568 23,490  
Cash and cash equivalents at beginning of period   $ 304,964   $ 193,513 304,964 193,513 193,513
Cash and cash equivalents at end of period $ 397,532   $ 217,003   397,532 217,003 $ 304,964
Supplemental Disclosure of Cash Flow Information:              
Cash paid for interest         5,179 5,179  
Cash paid for income taxes         11,944 0  
Supplemental Disclosure of Non-cash Investing and Financing Activities:              
2025 Notes converted to common stock         500 0  
Accrued interest income converted to long-term investments         $ 0 $ 799