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Debt - Schedule of Debt (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Dec. 31, 2024
Debt          
Total $ 261,000   $ 261,000   $ 453,500
Less: Unamortized debt discount and issuance costs (3,623)   (3,623)   (5,156)
Net carrying amount 257,377   257,377   448,344
Less: Current portion of long-term debt, net 0   0   (192,028)
Total long-term debt, net 257,377   257,377   256,316
Interest expense 4,015 $ 5,807 $ 13,389 $ 17,460  
HealthCare Royalty Partners          
Debt          
Maximum potential royalty payout     14.00%    
Increase in maximum potential payout percent     18.00%    
Maximum aggregate royalty payments     $ 225,000    
Maximum aggregate royalty payments     225,000    
Required payment for breach of agreement, payment one     125,000    
Payment for royalty agreement 36,700   36,700    
2025 Notes | Convertible senior notes          
Debt          
Total debt 0   0   192,500
Less: Unamortized debt discount and issuance costs         (472)
Net carrying amount         192,028
2028 Notes | Convertible senior notes          
Debt          
Total debt 261,000   261,000   261,000
Less: Unamortized debt discount and issuance costs (3,623)   (3,623)   (4,684)
Net carrying amount 257,377   257,377   256,316
Royalty Financing Agreement | Loans Payable [Member] | HealthCare Royalty Partners          
Debt          
Interest expense 1,600 $ 2,600 4,700 8,100  
Deferred Royalty obligations $ 64,300   64,300   $ 69,500
Royalty Payments     $ 9,500 $ 6,400  
Interest Rate of Deferred Royalty Obligation     9.74%