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Income Taxes - Additional Information (Details) - USD ($) $ in Millions | 12 Months Ended |
--- | --- | ---
Dec. 31, 2025 | Dec. 31, 2024
Income Taxes |  |
Accrued interest and penalties | $ 3.3 | $ 0.4
Federal |  |
Income Taxes |  |
Net operating loss carryforwards | 497.7 |
Net operating loss carryforwards do not expire | 448.2 |
Federal | Entasis Therapeutics Holdings Inc |  |
Income Taxes |  |
Net operating loss carryforwards | 146.5 |
Federal | La Jolla Pharmaceutical Company |  |
Income Taxes |  |
Net operating loss carryforwards | 351.2 |
State |  |
Income Taxes |  |
Net operating loss carryforwards | $ 1,028.9 |
Net operating loss carryforwards beginning date of expiry | Jan. 01, 2030 |
State | Research tax credit carryforward |  |
Income Taxes |  |
Tax credit carryforward amount | $ 33.6 |
Tax credit carryforward beginning date of expiry | Jan. 01, 2033 |

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