<SEC-DOCUMENT>0001628280-25-058328.txt : 20251219
<SEC-HEADER>0001628280-25-058328.hdr.sgml : 20251219
<ACCEPTANCE-DATETIME>20251219164802
ACCESSION NUMBER:		0001628280-25-058328
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20251217
FILED AS OF DATE:		20251219
DATE AS OF CHANGE:		20251219

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Chacon Quiros Juan Jose
		CENTRAL INDEX KEY:			0001742429
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38593
		FILM NUMBER:		251588224

	MAIL ADDRESS:	
		STREET 1:		C/O MOTIVA USA LLC
		STREET 2:		16192 COASTAL HIGHWAY
		CITY:			LEWES
		STATE:			DE
		ZIP:			19958

	FORMER NAME:	
		FORMER CONFORMED NAME:	Quiros Juan Jose Chacon
		DATE OF NAME CHANGE:	20180601

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ESTABLISHMENT LABS HOLDINGS INC.
		CENTRAL INDEX KEY:			0001688757
		STANDARD INDUSTRIAL CLASSIFICATION:	ORTHOPEDIC, PROSTHETIC & SURGICAL APPLIANCES & SUPPLIES [3842]
		ORGANIZATION NAME:           	08 Industrial Applications and Services
		EIN:				981436377
		STATE OF INCORPORATION:			D8
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		BUILDING B15 AND 25 COYOL FREE ZONE
		CITY:			ALAJUELA
		STATE:			G2
		ZIP:			20101
		BUSINESS PHONE:		50624342400

	MAIL ADDRESS:	
		STREET 1:		BUILDING B15 AND 25 COYOL FREE ZONE
		CITY:			ALAJUELA
		STATE:			G2
		ZIP:			20101
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>wk-form4_1766180879.xml
<DESCRIPTION>FORM 4
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0508</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2025-12-17</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001688757</issuerCik>
        <issuerName>ESTABLISHMENT LABS HOLDINGS INC.</issuerName>
        <issuerTradingSymbol>ESTA</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001742429</rptOwnerCik>
            <rptOwnerName>Chacon Quiros Juan Jose</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O MOTIVA USA LLC</rptOwnerStreet1>
            <rptOwnerStreet2>16192 COASTAL HIGHWAY</rptOwnerStreet2>
            <rptOwnerCity>LEWES</rptOwnerCity>
            <rptOwnerState>DE</rptOwnerState>
            <rptOwnerZipCode>19958</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <aff10b5One>0</aff10b5One>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Shares</value>
            </securityTitle>
            <transactionDate>
                <value>2025-12-17</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>G</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>50000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1078264</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnote</value>
                    <footnoteId id="F2"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Shares</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>214148</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes>
        <footnote id="F1">Represents a bona fide gift of shares to Chrysalis Enterprises LLC, an entity controlled by Manuel Enrique Chacon Quiros, the brother of the Reporting Person. The Reporting Person does not have a pecuniary interest in the shares held by Chrysalis Enterprises LLC and expressly disclaims beneficial ownership of these securities.</footnote>
        <footnote id="F2">The shares are held by Sariel Group Ltd. The Reporting Person is a shareholder of Sariel Group Ltd and has voting and dispositive power over the shares owned by Sariel Group Ltd. The Reporting Person disclaims beneficial ownership of the shares held by Sariel Group Ltd, except  to the extent of his pecuniary interest therein.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Rajbir S. Denhoy, Chief Financial Officer, by power of attorney</signatureName>
        <signatureDate>2025-12-19</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
