<SEC-DOCUMENT>0001209191-16-150672.txt : 20161116
<SEC-HEADER>0001209191-16-150672.hdr.sgml : 20161116
<ACCEPTANCE-DATETIME>20161116181235
ACCESSION NUMBER:		0001209191-16-150672
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20161116
FILED AS OF DATE:		20161116
DATE AS OF CHANGE:		20161116

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Pulse Biosciences, Inc.
		CENTRAL INDEX KEY:			0001625101
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			NV
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		849 MITTEN ROAD
		STREET 2:		SUITE 104
		CITY:			BURLINGAME
		STATE:			CA
		ZIP:			90401
		BUSINESS PHONE:		650-697-3939

	MAIL ADDRESS:	
		STREET 1:		849 MITTEN ROAD
		STREET 2:		SUITE 104
		CITY:			BURLINGAME
		STATE:			CA
		ZIP:			90401

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Electroblate, Inc.
		DATE OF NAME CHANGE:	20141113

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			LEVANDE ROBERT
		CENTRAL INDEX KEY:			0001240092

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37744
		FILM NUMBER:		162003435

	MAIL ADDRESS:	
		STREET 1:		8 EAST 67TH STREET
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10021
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>doc4.xml
<DESCRIPTION>FORM 4 SUBMISSION
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2016-11-16</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001625101</issuerCik>
        <issuerName>Pulse Biosciences, Inc.</issuerName>
        <issuerTradingSymbol>PLSE</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001240092</rptOwnerCik>
            <rptOwnerName>LEVANDE ROBERT</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>849 MITTEN ROAD, SUITE 104</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>BURLINGAME</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>94010</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <otherText>Chairman of the Board</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Warrant (right to buy)</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>5.00</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2016-11-16</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>85385</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.00</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2016-11-16</value>
            </exerciseDate>
            <expirationDate>
                <value>2021-05-13</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>85385</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>85385</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The warrant was originally issued to MDB Capital Group, LLC (&quot;MDB&quot;), pursuant to that certain Underwriting Agreement, dated May 17, 2016, between the Company and MDB as representative of the underwriters in connection with the Issuer's initial public offering, and subsequently re-issued to the Reporting Person.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Brian Dow, as Attorney-in-Fact</signatureName>
        <signatureDate>2016-11-16</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
