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Note 4 - Balance Sheet Components (Tables) | 9 Months Ended
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Sep. 30, 2025
Notes Tables |
Property, Plant and Equipment [Table Text Block] |
|  | September 30, |  |  | December 31, |
|  | 2025 |  |  | 2024 |
Leasehold improvements |  | $ | 2,519 |  |  | $ | 2,519 |
Laboratory equipment |  |  | 1,522 |  |  |  | 1,342 |
Furniture, fixtures and equipment |  |  | 966 |  |  |  | 966 |
Software |  |  | 283 |  |  |  | 272 |
Construction in progress |  |  | 46 |  |  |  | 29 |
Total property and equipment |  |  | 5,336 |  |  |  | 5,128 |
Less: Accumulated depreciation and amortization |  |  | (4,281 | ) |  |  | (3,968 | )
Total property and equipment, net |  | $ | 1,055 |  |  | $ | 1,160 |
Schedule of Finite-Lived Intangible Assets [Table Text Block] |
|  | September 30, |  |  | December 31, |
|  | 2025 |  |  | 2024 |
Acquired patents and licenses |  | $ | 8,005 |  |  | $ | 7,985 |
Less: Accumulated amortization |  |  | (7,264 | ) |  |  | (6,765 | )
Total intangible assets, net |  | $ | 741 |  |  | $ | 1,220 |
Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block] |
Years ending December 31: |  |  |  |
2025 (remaining 3 months) |  | $ | 166 |
2026 |  |  | 575 |
Total |  | $ | 741 |
Schedule of Accrued Liabilities [Table Text Block] |
|  | September 30, |  |  | December 31, |
|  | 2025 |  |  | 2024 |
Compensation expense |  | $ | 3,588 |  |  | $ | 4,097 |
Clinical trial fees and costs |  |  | 953 |  |  |  | 284 |
Professional fees |  |  | 311 |  |  |  | 564 |
Legal settlement |  |  | — |  |  |  | 1,196 |
Severance |  |  | — |  |  |  | 698 |
Other |  |  | 351 |  |  |  | 188 |
Total accrued expenses |  | $ | 5,203 |  |  | $ | 7,027 |

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