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Note 6 - Stockholders' Equity and Stock-based Compensation (Tables)

9 Months Ended

Sep. 30, 2025

Notes Tables

Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]

		Three Months Ended September 30,								Nine Months Ended September 30,
		2025				2024				2025				2024
Cost of product revenue		$	52			$	—			$	52			$	—
Research and development			2,232				1,108				7,329				3,058
Selling, general and administrative			3,333				1,874				9,106				3,735
Total stock-based compensation expense		$	5,617			$	2,982			$	16,487			$	6,793

		Three Months Ended September 30,								Nine Months Ended September 30,
		2025				2024				2025				2024
Time-based options		$	3,937			$	2,131			$	11,623			$	4,609
Performance-based options			—				5				—				27
Market-based options			1,577				788				4,581				1,978
ESPP			103				58				283				179
Total stock-based compensation expense		$	5,617			$	2,982			$	16,487			$	6,793

The 2015 Plan, 2017 Plan and Inducement Plan [Member]

Notes Tables

Share-Based Payment Arrangement, Option, Activity [Table Text Block]

		Stock Options Outstanding
		Number of shares				Weighted average exercise price				Weighted average remaining life (in years)
Balances — December 31, 2024			10,979,332			$	9.59				7.11
Options granted			2,884,343				18.67
Options exercised			(493,431	)			4.26
Options canceled			(66,500	)			13.13
Options expired			—				—
Balances — September 30, 2025			13,303,744			$	11.74				7.24
Exercisable — September 30, 2025			4,806,075			$	13.44				5.20

The 2017 Employee Stock Purchase Plan [Member]

Notes Tables

Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

		Three Months Ended September 30,								Nine Months Ended September 30,
		2025				2024				2025				2024
Expected term in years			0.5 - 1.0				0.5 - 1.0				0.5 - 1.0				0.5 - 1.0
Expected volatility			98%				98%				98%				98%
Risk-free interest rate			3.8% - 4.0%				4.4% - 5.3%				3.8% - 4.3%				4.9% - 5.3%
Dividend yield			—				—				—				—

Share-Based Payment Arrangement, Option [Member]

Notes Tables

Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

		Three Months Ended September 30,								Nine Months Ended September 30,
		2025				2024				2025				2024
Expected term in years			5.2 - 6.3				5.0 - 6.3				5.0 - 6.9				5.0 - 6.3
Expected volatility			93% - 95%				93% - 97%				93% - 100%				91% - 97%
Risk-free interest rate			4.0% - 4.1%				4.5%				4.0% - 4.6%				4.0% - 4.5%
Dividend yield			—				—				—				—

		Three Months Ended September 30,								Nine Months Ended September 30,
		2025				2024				2025				2024
Expected term in years			2.2 - 4.5				2.2 - 4.2				2.2 - 7.0				2.2 - 5.8
Expected volatility			90%				90%				90%				90%
Risk-free interest rate			3.9%				3.9%				3.9% - 4.6%				3.9% - 4.4%
Dividend yield			—				—				—				—

		Three Months Ended September 30,								Nine Months Ended September 30,
		2025				2024				2025				2024
Expected term in years			—				—				6.1 - 8.9				—
Expected volatility			—				—				90%				—
Risk-free interest rate			—				—				4.4% - 4.6%				—
Dividend yield			—				—				—				—

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