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Note 6 - Stockholders' Equity and Stock-based Compensation - Summary of Stock Option Activity (Details) - The 2015 Plan, 2017 Plan and Inducement Plan [Member]
 9 Months Ended 12 Months Ended
Sep. 30, 2025
$ / shares
shares
Dec. 31, 2024
$ / shares
shares
Options balances, number of shares (in shares) | shares 10,979,332  
Options balances, weighted average exercise price (in dollars per share) | $ / shares $ 9.59  
Options balances, weighted average remaining life (Year) 7 years 2 months 26 days 7 years 1 month 9 days
Options granted, number of shares (in shares) | shares 2,884,343  
Options granted, weighted average exercise price (in dollars per share) | $ / shares $ 18.67  
Options exercised, number of shares (in shares) | shares (493,431)  
Options exercised, weighted average exercise price (in dollars per share) | $ / shares $ 4.26  
Options canceled, number of shares (in shares) | shares (66,500)  
Options canceled, weighted average exercise price (in dollars per share) | $ / shares $ 13.13  
Options expired, number of shares (in shares) | shares 0  
Options expired, weighted average exercise price (in dollars per share) | $ / shares $ 0  
Options balances, number of shares (in shares) | shares 13,303,744 10,979,332
Options balances, weighted average exercise price (in dollars per share) | $ / shares $ 11.74 $ 9.59
Options exercisable, number of shares (in shares) | shares 4,806,075  
Options exercisable, weighted average exercise price (in dollars per share) | $ / shares $ 13.44  
Options exercisable, weighted average remaining life (Year) 5 years 2 months 12 days