<SEC-DOCUMENT>0000947871-25-000610.txt : 20250616
<SEC-HEADER>0000947871-25-000610.hdr.sgml : 20250616
<ACCEPTANCE-DATETIME>20250616073749
ACCESSION NUMBER:		0000947871-25-000610
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20250616
DATE AS OF CHANGE:		20250616

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Sionna Therapeutics, Inc.
		CENTRAL INDEX KEY:			0002036042
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-94871
		FILM NUMBER:		251048541

	BUSINESS ADDRESS:	
		STREET 1:		21 HICKORY DRIVE, SUITE 500
		CITY:			WALTHAM
		STATE:			MA
		ZIP:			02451
		BUSINESS PHONE:		617-819-2020

	MAIL ADDRESS:	
		STREET 1:		21 HICKORY DRIVE, SUITE 500
		CITY:			WALTHAM
		STATE:			MA
		ZIP:			02451

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Qatar Investment Authority
		CENTRAL INDEX KEY:			0001441449
		ORGANIZATION NAME:           	
		EIN:				000000000
		STATE OF INCORPORATION:			S3
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G

	BUSINESS ADDRESS:	
		STREET 1:		OOREDOO TOWER (BUILDING 14),
		STREET 2:		AL DAFNA ST (STREET 801)
		CITY:			DOHA
		STATE:			S3
		ZIP:			QATAR
		BUSINESS PHONE:		974 441 4466

	MAIL ADDRESS:	
		STREET 1:		P.O. BOX 23224
		CITY:			DOHA
		STATE:			S3
		ZIP:			QATAR
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G
<SEQUENCE>1
<FILENAME>primary_doc.xml
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      <securitiesClassTitle>Common Stock SH</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>06/11/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0002036042</issuerCik>
        <issuerName>Sionna Therapeutics Inc</issuerName>
        <issuerCusip>829401108</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>21 Hickory Drive, Suite 500</com:street1>
          <com:city>Waltham</com:city>
          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>02451</com:zipCode>
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      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>2209775.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>5.0</classPercent>
      <typeOfReportingPerson>OO</typeOfReportingPerson>
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    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Q Healthcare Holding LLC</reportingPersonName>
      <citizenshipOrOrganization>S3</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
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        <issuerName>Sionna Therapeutics Inc</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>21 Hickory Drive, Suite 500, Waltham, MA 02451, US</issuerPrincipalExecutiveOfficeAddress>
      </item1>
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        <filingPersonName>Qatar Investment Authority  |  Q Healthcare Holding LLC</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>Qatar Investment Authority - Ooredoo Tower (Building 14), Al Dafna Street (Street 801), Al Dafna (Zone 61), Doha, Qatar  |  Q Healthcare Holding LLC - Ooredoo Tower (Building 14) Al Dafna Street (Street 801) Al Dafna (Zone 61), Doha, Qatar</principalBusinessOfficeOrResidenceAddress>
        <citizenship>Qatar Investment Authority - Qatar  Q Healthcare Holding LLC - Qatar</citizenship>
      </item2>
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        <notApplicableFlag>N</notApplicableFlag>
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          <sharedPowerOrDirectToDispose>0</sharedPowerOrDirectToDispose>
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      </item4>
      <item5>
        <notApplicableFlag>Y</notApplicableFlag>
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      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
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    </items>
    <signatureInformation>
      <reportingPersonName>Qatar Investment Authority</reportingPersonName>
      <signatureDetails>
        <signature>Andrew Watkins</signature>
        <title>Head of Compliance</title>
        <date>06/15/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Q Healthcare Holding LLC</reportingPersonName>
      <signatureDetails>
        <signature>Andrew Watkins</signature>
        <title>Head of Compliance</title>
        <date>06/15/2025</date>
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</SEC-DOCUMENT>
