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Note 9 - Warrants - Summary of Warrant Activity (Details) - $ / shares | 12 Months Ended
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Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019
Outstanding at beginning of year (in shares) | 79,100 | 3,959,005 | 4,080,005
Outstanding, weighted average exercise price (in dollars per share) | $ 4.75 | $ 4.33 | $ 4.35
Exercised, number of shares (in shares) | (79,100) | (3,879,905) | (121,000)
Exercised, weighted average exercise price (in dollars per share) | $ 4.75 | $ 4.33 | $ 4.75
Outstanding, number of shares (in shares) | 0 | 79,100 | 3,959,005
Outstanding, weighted average exercise price (in dollars per share) | $ 0 | $ 4.75 | $ 4.33

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- Definition The number of warrants or rights exercised during period. + References No definition available. + Details
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Namespace Prefix: | blfs_
Data Type: | xbrli:sharesItemType
Balance Type: | na
Period Type: | duration

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- Definition Exercise price per share of warrants or rights exercised during period. + References No definition available. + Details
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Namespace Prefix: | blfs_
Data Type: | dtr-types:perShareItemType
Balance Type: | na
Period Type: | duration

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- Definition Exercise price per share or per unit of warrants or rights outstanding. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 10 -Section 50 -Paragraph 3 -URI http://asc.fasb.org/extlink&oid=123467817&loc=d3e21475-112644 + Details
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Namespace Prefix: | us-gaap_
Data Type: | dtr-types:perShareItemType
Balance Type: | na
Period Type: | instant

X
- Definition Number of warrants or rights outstanding. + References No definition available. + Details
Name: | us-gaap_ClassOfWarrantOrRightOutstanding
Namespace Prefix: | us-gaap_
Data Type: | xbrli:sharesItemType
Balance Type: | na
Period Type: | instant