<SEC-DOCUMENT>0000919574-25-004980.txt : 20250815
<SEC-HEADER>0000919574-25-004980.hdr.sgml : 20250815
<ACCEPTANCE-DATETIME>20250815213302
ACCESSION NUMBER:		0000919574-25-004980
CONFORMED SUBMISSION TYPE:	144
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20250815
DATE AS OF CHANGE:		20250815

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BIOLIFE SOLUTIONS INC
		CENTRAL INDEX KEY:			0000834365
		STANDARD INDUSTRIAL CLASSIFICATION:	ELECTROMEDICAL & ELECTROTHERAPEUTIC APPARATUS [3845]
		ORGANIZATION NAME:           	08 Industrial Applications and Services
		EIN:				943076866
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		144
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	001-36362
		FILM NUMBER:		251226148

	BUSINESS ADDRESS:	
		STREET 1:		3303 MONTE VILLA PARKWAY
		STREET 2:		SUITE 310
		CITY:			BOTHELL
		STATE:			WA
		ZIP:			98021
		BUSINESS PHONE:		4254011400

	MAIL ADDRESS:	
		STREET 1:		3303 MONTE VILLA PARKWAY
		STREET 2:		SUITE 310
		CITY:			BOTHELL
		STATE:			WA
		ZIP:			98021

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	BIOLIFE SOLUTION INC
		DATE OF NAME CHANGE:	20030113

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CRYOMEDICAL SCIENCES INC
		DATE OF NAME CHANGE:	19920703

REPORTING-OWNER:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Casdin Partners Master Fund, L.P.
		CENTRAL INDEX KEY:			0001534265
		ORGANIZATION NAME:           	
		EIN:				981020311
		STATE OF INCORPORATION:			E9
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		144

	BUSINESS ADDRESS:	
		ADDRESS IS A NON US LOCATION: 	YES
		STREET 1:		WALKER HOUSE
		STREET 2:		87 MARY STREET
		CITY:			GEORGE TOWN
		PROVINCE COUNTRY:   	E9
		BUSINESS PHONE:		212.300.5575

	MAIL ADDRESS:	
		ADDRESS IS A NON US LOCATION: 	YES
		STREET 1:		WALKER HOUSE
		STREET 2:		87 MARY STREET
		CITY:			GEORGE TOWN
		PROVINCE COUNTRY:   	E9
</SEC-HEADER>
<DOCUMENT>
<TYPE>144
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <!-- Field: Pseudo-Tag; ID: Name; Data: Casdin Partners Master Fund, L.P. -->
          <cik>0001534265</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0000834365</issuerCik>
      <issuerName>BioLife Solutions, Inc.</issuerName>
      <secFileNumber>001-36362</secFileNumber>
      <issuerAddress>
        <com:street1>3303 Monte Villa Parkway</com:street1>
        <com:street2>Suite 310</com:street2>
        <com:city>Bothell</com:city>
        <com:stateOrCountry>WA</com:stateOrCountry>
        <com:zipCode>98021</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>425-402-1400</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Casdin Partners Master Fund, L.P.</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>10% Shareholder</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Common Stock, par value $0.001 per share</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>BMO Capital Markets</name>
        <address>
          <com:street1>151 W 42nd St</com:street1>
          <com:city>New York</com:city>
          <com:stateOrCountry>NY</com:stateOrCountry>
          <com:zipCode>10036</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>500000</noOfUnitsSold>
      <aggregateMarketValue>12660000.00</aggregateMarketValue>
      <noOfUnitsOutstanding>47905265</noOfUnitsOutstanding>
      <approxSaleDate>08/15/2025</approxSaleDate>
      <securitiesExchangeName>NASDAQ</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Common Stock, par value $0.001 per share</securitiesClassTitle>
      <acquiredDate>07/02/2020</acquiredDate>
      <natureOfAcquisitionTransaction>Purchase</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>The shares were purchased directly from the issuer.</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>250000</amountOfSecuritiesAcquired>
      <paymentDate>07/02/2020</paymentDate>
      <natureOfPayment>Cash</natureOfPayment>
    </securitiesToBeSold>
    <securitiesToBeSold>
      <securitiesClassTitle>Common Stock, par value $0.001 per share</securitiesClassTitle>
      <acquiredDate>12/16/2020</acquiredDate>
      <natureOfAcquisitionTransaction>Purchase</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>The shares were purchased directly from a shareholder of the issuer.</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>100000</amountOfSecuritiesAcquired>
      <paymentDate>12/16/2020</paymentDate>
      <natureOfPayment>Cash</natureOfPayment>
    </securitiesToBeSold>
    <securitiesToBeSold>
      <securitiesClassTitle>Common Stock, par value $0.001 per share</securitiesClassTitle>
      <acquiredDate>04/30/2024</acquiredDate>
      <natureOfAcquisitionTransaction>Purchase</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>The shares were purchased directly from a shareholder of the issuer.</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>150000</amountOfSecuritiesAcquired>
      <paymentDate>04/30/2024</paymentDate>
      <natureOfPayment>Cash</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Casdin Partners Master Fund, L.P.</name>
        <address>
          <com:street1>1350 Avenue of the Americas</com:street1>
          <com:street2>Suite 2600</com:street2>
          <com:city>New York</com:city>
          <com:stateOrCountry>NY</com:stateOrCountry>
          <com:zipCode>10019</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common Stock, par value $0.001 per share</securitiesClassTitle>
      <saleDate>08/11/2025</saleDate>
      <amountOfSecuritiesSold>500000</amountOfSecuritiesSold>
      <grossProceeds>11300000.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Casdin Partners Master Fund, L.P.</name>
        <address>
          <com:street1>1350 Avenue of the Americas</com:street1>
          <com:street2>Suite 2600</com:street2>
          <com:city>New York</com:city>
          <com:stateOrCountry>NY</com:stateOrCountry>
          <com:zipCode>10019</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common Stock, par value $0.001 per share</securitiesClassTitle>
      <saleDate>06/10/2025</saleDate>
      <amountOfSecuritiesSold>1000000</amountOfSecuritiesSold>
      <grossProceeds>23800000.00</grossProceeds>
    </securitiesSoldInPast3Months>
    <noticeSignature>
      <noticeDate>08/15/2025</noticeDate>
      <signature>/s/ Eli Casdin</signature>
    </noticeSignature>
  </formData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
