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Income Tax (Tables)
12 Months Ended
Dec. 31, 2021
Schedule of Income Loss Before Income Taxes
Loss before income taxes consisted of the following:
 
    
Year Ended December 31,
 
    
2021
    
2020
    
2019
 
United States
   $ (4,092,348    $ (1,742,747    $ (3,290,679
Brazil
     (11,774,438      (7,883,195      (4,394,840
    
 
 
    
 
 
    
 
 
 
Total
  
$
(15,866,786
  
$
(9,625,942
  
$
(7,685,519
    
 
 
    
 
 
    
 
 
 
Summary Of Deferred Tax Assets And Liabilities
The tax effects of temporary differences and carryforwards that give rise to significant portions of deferred tax assets and liabilities consisted of the following:
 
    
December 31,
 
    
2021
   
2020
   
2019
 
Deferred tax assets:
                        
Net operating loss carryforwards
(i)
  
$
12,555,225    
$
7,615,613    
$
4,477,240  
Federal R&D Credit
(ii)
     351,985       340,162       331,741  
Accrued benefits
     63,153       9,892       14,715  
Uncertain Tax Position—R&D Reserve
     (70,397     (68,032     (66,349
    
 
 
   
 
 
   
 
 
 
Total deferred tax assets
  
 
12,899,966
 
 
 
7,897,635
 
 
 
4,757,347
 
    
 
 
   
 
 
   
 
 
 
Less valuation allowance
  
 
(12,899,966
 
 
(7,897,635
 
 
(4,757,347
    
 
 
   
 
 
   
 
 
 
Net deferred tax assets
  
$
—  
 
 
$
—  
 
 
$
—  
 
    
 
 
   
 
 
   
 
 
 
 
(i)
Net operating losses carryforwards do not expire.
(ii)
These credits expire after 20 years after their initial recognition if the entity is not able to utilize them.
Summary Of Income Tax
Income taxes consisted of the following:
 
    
United
States

(21%)
   
State and
local

(5%)
   
Brazil

(34%)
   
Total
   
Valuation
allowance
    
Total
 
2021
                                                 
Current
     —         —         —         —         —          —    
Deferred
   $ (871,006   $ (204,567   $ (3,929,123   $ (5,004,696   $ 5,004,696        —    
2020
                                                 
Current
     —         —         —         —         —          —    
Deferred
   $ (374,301   $ (87,114   $ (2,680,556   $ (3,141,971   $ 3,141,971        —    
2019
                                                 
Current
     —         —         —         —         —          —    
Deferred
   $ (734,239   $ (164,534   $ (1,483,969   $ (2,382,742   $ 2,382,742        —    
Summary Of Income Tax Rate Reconciliation
A reconciliation of the statutory U.S. federal tax rate and our effective tax rate is as follows:
 
    
Year Ended
December 31,
 
    
2021
   
2020
   
2019
 
Statutory U.S. federal tax rate
  
 
21
 
 
21
 
 
21
State and local taxes
     5     5     5
Reserves
     0     0     1
    
 
 
   
 
 
   
 
 
 
Valuation allowance
  
 
-26
 
 
-26
 
 
-27
    
 
 
   
 
 
   
 
 
 
Effective tax rate
  
 
0
 
 
0
 
 
0