EXHIBIT 99.1

SANDERLING VENTURE PARTNERS VI, L.P.




By:  Middleton, McNeil, Mills & Associates VI, LLC

By:  /s/ Fred A. Middleton
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         Fred A. Middleton
         Managing Director




SANDERLING VI BETEILIGUNGS GMBH & CO. KG

By:  Middleton, McNeil, Mills & Associates VI, LLC

By:  /s/ Fred A. Middleton
     ------------------------------------------------
         Fred A. Middleton
         Managing Director




SANDERLING VENTURES MANAGEMENT VI

By:  /s/ Fred A. Middleton
     ------------------------------------------------
         Fred A. Middleton
         Owner




SANDERLING VI LIMITED PARTNERSHIP

By:  Middleton, McNeil, Mills & Associates VI, LLC

By:  /s/ Fred A. Middleton
     ------------------------------------------------
         Fred A. Middleton
         Managing Director




SANDERLING VENTURE PARTNERS VI CO-INVESTMENT FUND, L.P.

By:  Middleton, McNeil, Mills & Associates VI, LLC

By:  /s/ Fred A. Middleton
     ------------------------------------------------
         Fred A. Middleton
         Managing Director