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CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Revenues:        
Net product sales $ 70,139 $ 67,687 $ 138,564 $ 132,189
Collaborative licensing and milestone revenue 130 1,356 336 1,713
Royalty revenue 665 597 1,317 1,212
Total revenues 70,934 69,640 140,217 135,114
Operating expenses:        
Cost of goods sold 23,811 23,053 48,392 43,331
Research and development 18,856 9,362 35,487 18,855
Selling, general and administrative 39,552 43,669 81,672 81,626
Product discontinuation 4,495 0 4,495 0
Total operating expenses 86,714 76,084 170,046 143,812
Loss from operations (15,780) (6,444) (29,829) (8,698)
Other (expense) income:        
Interest income 1,224 324 1,738 576
Interest expense (5,226) (1,733) (7,815) (3,601)
Loss on early extinguishment of debt (11) 0 (3,732) 0
Other, net 80 (47) 89 1
Total other expense, net (3,933) (1,456) (9,720) (3,024)
Loss before income taxes (19,713) (7,900) (39,549) (11,722)
Income tax expense (30) (58) (60) (90)
Net loss $ (19,743) $ (7,958) $ (39,609) $ (11,812)
Net loss per share:        
Basic and diluted net loss per common share (in USD per share) $ (0.49) $ (0.21) $ (1.01) $ (0.32)
Weighted average common shares outstanding:        
Basic and diluted (in shares) 40,160 37,181 39,079 37,101