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INCOME TAXES (Tables)
12 Months Ended
Dec. 31, 2017
Income Tax Disclosure [Abstract]  
Schedule of reconciliation of income taxes at the U.S. Federal statutory rate to the provision for income taxes
A reconciliation of income taxes at the U.S. federal statutory rate to the provision for income taxes is as follows:
 
Year Ended December 31,
 
2017
 
2016
 
2015
U.S. federal statutory rate
35.00
 %
 
35.00
 %
 
35.00
 %
State taxes
2.26
 %
 
2.20
 %
 
0.71
 %
Foreign taxes
(1.28
)%
 
(0.81
)%
 
12.03
 %
Change in valuation allowance
4.58
 %
 
(43.96
)%
 
10.32
 %
Stock-based compensation
(1.21
)%
 
(0.54
)%
 
7.26
 %
Tax credits
4.96
 %
 
8.77
 %
 
(30.63
)%
Interest expense
2.90
 %
 
5.75
 %
 
(37.57
)%
Effect of rate changes
(130.88
)%
 
(4.65
)%
 
 %
Convertible senior notes refinancing
6.55
 %
 
 %
 
 %
Effect of the adoption of ASU 2016-09
68.89
 %
 
 %
 
 %
Other
7.90
 %
 
(2.04
)%
 
15.33
 %
Effective tax rate
(0.33
)%
 
(0.28
)%
 
12.45
 %
Schedule of significant components of the Company's deferred tax assets
Deferred taxes reflect the tax effects of the differences between the amounts recorded as assets and liabilities for financial reporting purposes and the comparable amounts recorded for income tax purposes. Significant components of the Company’s deferred tax assets and liabilities at December 31, 2017 and 2016 are as follows (in thousands):
 
December 31,
 
2017
 
2016
Deferred tax assets:
 
 
 
Net operating loss carry-forwards
$
95,067

 
$
96,163

Federal and state credits
15,048

 
13,724

Depreciation and amortization
2,593

 
2,604

Accruals and reserves
2,743

 
4,672

Deferred revenue
1,841

 
3,023

Stock based compensation
16,925

 
21,890

Inventory
552

 
9,811

Other
139

 
52

Total deferred tax assets
134,908

 
151,939

Deferred tax liabilities:
 
 
 
Discount on convertible senior notes
(14,678
)
 
(3,186
)
 
120,230

 
148,753

Less: valuation allowance
(120,230
)
 
(148,753
)
Net deferred tax assets
$

 
$