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FIXED ASSETS (Tables)
 6 Months Ended
Jun. 30, 2018
Property, Plant and Equipment [Abstract]  
Schedule of fixed assets summarized by major category
Fixed assets, summarized by major category, consist of the following (in thousands):
 
June 30,
 
December 31,
 
2018
 
2017
Machinery and laboratory equipment
$
41,809

 
$
39,002

Leasehold improvements
34,932

 
34,933

Computer equipment and software
7,448

 
7,086

Office furniture and equipment
1,420

 
1,603

Construction in progress
79,670

 
73,632

        Total
165,279

 
156,256

Less: accumulated depreciation
(54,003
)
 
(49,210
)
        Fixed assets, net
$
111,276

 
$
107,046