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CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Revenues:        
Net product sales $ 80,717 $ 70,139 $ 155,004 $ 138,564
Collaborative licensing and milestone revenue 3,000 130 3,000 336
Royalty revenue 390 665 710 1,317
Total revenues 84,107 70,934 158,714 140,217
Operating expenses:        
Cost of goods sold 20,916 23,811 43,801 48,392
Research and development 12,239 18,856 26,617 35,487
Selling, general and administrative 44,249 39,552 88,439 81,672
Product discontinuation 162 4,495 252 4,495
Total operating expenses 77,566 86,714 159,109 170,046
Income (loss) from operations 6,541 (15,780) (395) (29,829)
Other (expense) income:        
Interest income 1,533 1,224 2,906 1,738
Interest expense (5,397) (5,226) (10,553) (7,815)
Loss on early extinguishment of debt 0 (11) 0 (3,732)
Other, net (78) 80 (4) 89
Total other expense, net (3,942) (3,933) (7,651) (9,720)
Income (loss) before income taxes 2,599 (19,713) (8,046) (39,549)
Income tax expense (35) (30) (70) (60)
Net income (loss) $ 2,564 $ (19,743) $ (8,116) $ (39,609)
Net income (loss) per share:        
Basic and diluted net loss per common share (in USD per share) $ 0.06 $ (0.49) $ (0.20) $ (1.01)
Weighted average common shares outstanding:        
Basic (in shares) 40,796 40,160 40,751 39,079
Diluted (in shares) 41,694 40,160 40,751 39,079