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Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands | Total | Convertible debt | Convertible Senior Notes Due 2022 [Member] | Common Stock | Additional Paid-In Capital | Additional Paid-In Capital Convertible debt | Additional Paid-In Capital Convertible Senior Notes Due 2022 [Member] | Accumulated Deficit | Accumulated Other Comprehensive Income
--- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Balances at Dec. 31, 2015 | $ 218,392 |  |  | $ 37 | $ 526,696 |  |  | $ (308,289) | $ (52)
Balances (in shares) at Dec. 31, 2015 |  |  |  | 36,848,000 |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |  |
Exercise of stock options | 5,770 |  |  |  | 5,770 |  |  |  |
Exercise of stock options (in shares) |  |  |  | 518,000 |  |  |  |  |
Vested restricted stock units | 0 |  |  |  |  |  |  |  |
Vested restricted stock units (in shares) |  |  |  | 62,000 |  |  |  |  |
Shares issued under employee stock purchase plan | 1,495 |  |  |  | 1,495 |  |  |  |
Shares issued under employee stock purchase plan (in shares) |  |  |  | 53,000 |  |  |  |  |
Stock-based compensation | 31,248 |  |  |  | 31,248 |  |  |  |
Equity component of convertible senior notes, net of issuance costs | (2) |  |  |  | (2) |  |  |  |
Net unrealized gain (loss) on investments | 22 |  |  |  |  |  |  |  | 22
Net loss | (37,949) |  |  |  |  |  |  | (37,949) |
Balances at Dec. 31, 2016 | 218,976 |  |  | $ 37 | 565,207 |  |  | (346,238) | (30)
Balances (in shares) at Dec. 31, 2016 |  |  |  | 37,481,000 |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |  |
Net loss | (19,866) |  |  |  |  |  |  |  |
Balances at Dec. 31, 2016 | 218,976 |  |  | $ 37 | 565,207 |  |  | (346,238) | (30)
Balances (in shares) at Dec. 31, 2016 |  |  |  | 37,481,000 |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |  |
Exercise of stock options | 6,778 |  |  | $ 1 | 6,777 |  |  |  |
Exercise of stock options (in shares) |  |  |  | 540,000 |  |  |  |  |
Vested restricted stock units | 0 |  |  |  |  |  |  |  |
Vested restricted stock units (in shares) |  |  |  | 101,000 |  |  |  |  |
Shares issued under employee stock purchase plan | 1,862 |  |  |  | 1,862 |  |  |  |
Shares issued under employee stock purchase plan (in shares) |  |  |  | 57,000 |  |  |  |  |
Stock-based compensation | 31,601 |  |  |  | 31,601 |  |  |  |
Issuance of common stock upon conversion of 2019 convertible senior notes | 120,960 |  |  | $ 3 | 120,957 |  |  |  |
Issuance of common stock upon conversion of 2019 convertible senior notes (in shares) |  |  |  | 2,490,000 |  |  |  |  |
Equity component of convertible senior notes, net of issuance costs |  | $ (126,328) | $ 68,669 |  |  | $ (126,328) | $ 68,669 |  |
Net unrealized gain (loss) on investments | (424) |  |  |  |  |  |  |  | (424)
Net loss | (42,611) |  |  |  |  |  |  | (42,611) |
Balances at Dec. 31, 2017 | 279,483 |  |  | $ 41 | 669,032 |  |  | (389,136) | (454)
Balances (in shares) at Dec. 31, 2017 |  |  |  | 40,669,000 |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |  |
Cumulative effect adjustment of the adoption of Accounting Standards Update 2016-09 (Note 3) |  |  |  |  | 287 |  |  | (287) |
Net loss | (10,680) |  |  |  |  |  |  |  |
Balances at Dec. 31, 2017 | 279,483 |  |  | $ 41 | 669,032 |  |  | (389,136) | (454)
Balances (in shares) at Dec. 31, 2017 |  |  |  | 40,669,000 |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |  |
Exercise of stock options | 7,170 |  |  | $ 0 | 7,170 |  |  |  |
Exercise of stock options (in shares) |  |  |  | 333,000 |  |  |  |  |
Vested restricted stock units | 0 |  |  | $ 0 |  |  |  |  |
Vested restricted stock units (in shares) |  |  |  | 156,000 |  |  |  |  |
Shares issued under employee stock purchase plan | $ 1,784 |  |  |  | 1,784 |  |  |  |
Shares issued under employee stock purchase plan (in shares) | 224,887 |  |  | 65,000 |  |  |  |  |
Stock-based compensation | $ 31,725 |  |  |  | 31,725 |  |  |  |
Net unrealized gain (loss) on investments | 174 |  |  |  |  |  |  |  | 174
Net loss | (471) |  |  |  |  |  |  | (471) |
Balances at Dec. 31, 2018 | 321,226 |  |  | $ 41 | 709,691 |  |  | (388,226) | $ (280)
Balances (in shares) at Dec. 31, 2018 |  |  |  | 41,223,000 |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |  |
Cumulative effect adjustment of the adoption of Accounting Standards Update 2016-09 (Note 3) | 1,361 |  |  |  |  |  |  | 1,361 |
Net loss | $ 2,564 |  |  |  |  |  |  |  |
Cumulative effect adjustment of the adoption of Accounting Standards Update 2016-09 (Note 3) |  |  |  |  | $ (20) |  |  | $ 20 |

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