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FIXED ASSETS (Tables)
 12 Months Ended
Dec. 31, 2018
Property, Plant and Equipment [Abstract]  
Schedule of fixed assets summarized by major category
Fixed assets, net, summarized by major category, consist of the following (in thousands):
 
December 31,
 
2018
 
2017
Machinery and laboratory equipment
$
67,431

 
$
39,002

Leasehold improvements
57,955

 
34,933

Computer equipment and software
8,131

 
7,086

Office furniture and equipment
1,548

 
1,603

Construction in progress
35,163

 
73,632

 Total
170,228

 
156,256

Less: accumulated depreciation
(61,558
)
 
(49,210
)
Fixed assets, net
$
108,670

 
$
107,046