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FIXED ASSETS (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
FIXED ASSETS      
Total $ 170,228 $ 156,256  
Less accumulated depreciation (61,558) (49,210)  
Fixed assets, net 108,670 107,046  
Depreciation expense 13,200 13,800 $ 12,800
Capitalized interest 689 1,101 $ 1,491
Foreign Property, Plant and Equipment, Net 64,600 59,800  
Asset Retirement Obligation 2,200 1,500  
Increase (Decrease) in Asset Retirement Obligations 400    
Asset Retirement Obligation, Accretion Expense 100    
Manufacturing and laboratory equipment      
FIXED ASSETS      
Total 67,431 39,002  
Leasehold improvements      
FIXED ASSETS      
Total 57,955 34,933  
Computer equipment and software      
FIXED ASSETS      
Total 8,131 7,086  
Office furniture and equipment      
FIXED ASSETS      
Total 1,548 1,603  
Construction in progress      
FIXED ASSETS      
Total $ 35,163 $ 73,632