<SEC-DOCUMENT>0001315863-19-000503.txt : 20190605
<SEC-HEADER>0001315863-19-000503.hdr.sgml : 20190605
<ACCEPTANCE-DATETIME>20190605125731
ACCESSION NUMBER:		0001315863-19-000503
CONFORMED SUBMISSION TYPE:	SC 13D/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20190605
DATE AS OF CHANGE:		20190605
GROUP MEMBERS:		CONSONANCE CAPMAN GP LLC
GROUP MEMBERS:		MITCHELL BLUTT

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Pacira BioSciences, Inc.
		CENTRAL INDEX KEY:			0001396814
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				510619477
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13D/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-86096
		FILM NUMBER:		19879248

	BUSINESS ADDRESS:	
		STREET 1:		5 SYLVAN WAY
		STREET 2:		SUITE 300
		CITY:			PARSIPPANY
		STATE:			NJ
		ZIP:			07054
		BUSINESS PHONE:		973-254-3560

	MAIL ADDRESS:	
		STREET 1:		5 SYLVAN WAY
		STREET 2:		SUITE 300
		CITY:			PARSIPPANY
		STATE:			NJ
		ZIP:			07054

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Pacira Pharmaceuticals, Inc.
		DATE OF NAME CHANGE:	20101029

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PACIRA INC
		DATE OF NAME CHANGE:	20080318

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Blue Acquisition Corp
		DATE OF NAME CHANGE:	20070418

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Consonance Capital Management LP
		CENTRAL INDEX KEY:			0001544773
		IRS NUMBER:				260294313
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13D/A

	BUSINESS ADDRESS:	
		STREET 1:		1370 AVENUE OF THE AMERICAS
		STREET 2:		SUITE 3301
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10019
		BUSINESS PHONE:		212.660-8062

	MAIL ADDRESS:	
		STREET 1:		1370 AVENUE OF THE AMERICAS
		STREET 2:		SUITE 3301
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10019
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13D/A
<SEQUENCE>1
<FILENAME>sc_13da_consonance.htm
<TEXT>
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  <div style="text-align: center;"><font style="font-size: 18pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">UNITED STATES</font></div>
  <div style="text-align: center;"><font style="font-size: 18pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">SECURITIES AND EXCHANGE COMMISSION</font></div>
  <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">WASHINGTON, D.C. 20549</font></div>
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  <div style="text-align: center; margin-top: 12pt;"><font style="font-size: 18pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">SCHEDULE 13D</font></div>
  <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
  <div style="text-align: center; margin-top: 12pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;<font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">Under the Securities Exchange
        Act of 1934</font></font></div>
  <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">(Amendment No.&#160;1)*</font></div>
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  <div style="text-align: center; margin-top: 12pt;"><font style="font-size: 18pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">Pacira BioSciences, Inc.</font></div>
  <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">(Name of Issuer)</font></div>
  <div style="text-align: center; margin-top: 12pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">Common Stock, $0.001 par value</font></div>
  <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">(Title of Class&#160;of Securities)</font></div>
  <div style="text-align: center; margin-top: 12pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">695127100</font></div>
  <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">(CUSIP NUMBER)</font></div>
  <div style="text-align: center; margin-top: 12pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">Edward Cook</font></div>
  <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">1370 Avenue of the Americas, 33rd Floor</font></div>
  <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">New York NY 10019</font></div>
  <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">(212) 660-8060</font></div>
  <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">(Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)</font></div>
  <div style="text-align: center; margin-top: 12pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">June 3, 2019</font></div>
  <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">(Date of event which requires filing of this statement)</font></div>
  <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
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  <div style="text-align: left; margin-top: 12pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">If the filing person has previously filed a statement on Schedule 13G to report the acquisition which is the subject of this
      Schedule 13D, and is filing this schedule because of Rule 13d-1(e), 13d-1(f) or 13d-1(g) check the following box &#160;&#160;&#9746;.</font></div>
  <div style="text-align: left; margin-top: 12pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">The information required in the remainder of this cover page shall not be deemed to be &#8220;filed&#8221; for the purpose of Section&#160;18 of
      the Securities Exchange Act of 1934, as amended (the &#8220;Act&#8221;), or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act.</font></div>
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        <td style="width: 20%; vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">CUSIP&#160;No. 695127100</font></div>
        </td>
        <td style="width: 20%; vertical-align: bottom;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td style="width: 20%; vertical-align: bottom;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">13D</font></div>
        </td>
        <td style="width: 20%; vertical-align: bottom;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
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          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;1&#160;</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">NAME OF REPORTING PERSONS</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Consonance Capital Management LP</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;2</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">(a)&#160;&#160;&#9744;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;(b)&#160;&#160;&#9744;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
      </tr>
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          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;3</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SEC USE ONLY</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
      </tr>
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          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;4</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SOURCE OF FUNDS*</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">AF</font></div>
        </td>
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          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;5</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) or 2(e)</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#9744;</font></div>
        </td>
      </tr>
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        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;6</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">CITIZENSHIP OR PLACE OF ORGANIZATION</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Delaware</font></div>
        </td>
      </tr>
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        <td colspan="3" rowspan="4" style="vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">NUMBER&#160;OF</font></div>
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SHARES</font></div>
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">BENEFICIALLY</font></div>
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">OWNED&#160;BY</font></div>
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">EACH</font></div>
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">REPORTING</font></div>
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">PERSON</font></div>
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">WITH</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td style="width: 3%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 7%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;7&#160;</font></div>
        </td>
        <td style="width: 2.81%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 71%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SOLE VOTING POWER</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">0</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 3%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 7%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;8</font></div>
        </td>
        <td style="width: 2.81%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 71%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SHARED VOTING POWER</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;">3,205,559<font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;"><br>
            </font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 3%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 7%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;9</font></div>
        </td>
        <td style="width: 2.81%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 71%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SOLE DISPOSITIVE POWER</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">0</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 3%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 7%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">10</font></div>
        </td>
        <td style="width: 2.81%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 71%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SHARED DISPOSITIVE POWER</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;">3,205,559<font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;"> </font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">11</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;">3,205,559</div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">12</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#9744;</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">13</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">7.8%</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">14</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">TYPE OF REPORTING PERSON*</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">IA, PN</font></div>
        </td>
      </tr>

  </table>
  <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
  <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%;" id="z683fe94b1775409c94e1a466aaafb308">

      <tr>
        <td style="width: 2%; vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">*</font></div>
        </td>
        <td style="width: 98%; vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SEE INSTRUCTIONS BEFORE FILLING OUT</font></div>
        </td>
      </tr>

  </table>
  <div style="margin-top: 6pt; margin-bottom: 6pt;"><br>
  </div>
  <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
    <div style="page-break-after:always;" id="DSPFPageBreak">
      <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
  </div>
  <div style="margin-top: 6pt; margin-bottom: 6pt;"><br>
  </div>
  <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
  <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%;" id="z6ffde3730aca437391728dbcaca05fa2">

      <tr>
        <td style="width: 20%; vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">CUSIP&#160;No. 695127100</font></div>
        </td>
        <td style="width: 20%; vertical-align: bottom;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td style="width: 20%; vertical-align: bottom;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">13D</font></div>
        </td>
        <td style="width: 20%; vertical-align: bottom;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td style="width: 20%; vertical-align: bottom;">&#160;</td>
      </tr>

  </table>
  <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
  <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%;" id="z9007bc8440c84afd8ff838d57998a728">

      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;1&#160;</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">NAME OF REPORTING PERSONS</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Consonance Capman GP LLC</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;2</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">(a)&#160;&#160;&#9744;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;(b)&#160;&#160;&#9744;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;3</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SEC USE ONLY</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;4</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SOURCE OF FUNDS*</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">AF</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;5</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) or 2(e)</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#9744;</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;6</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">CITIZENSHIP OR PLACE OF ORGANIZATION</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Delaware</font></div>
        </td>
      </tr>
      <tr>
        <td colspan="3" rowspan="4" style="vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">NUMBER&#160;OF</font></div>
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SHARES</font></div>
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">BENEFICIALLY</font></div>
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">OWNED&#160;BY</font></div>
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">EACH</font></div>
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">REPORTING</font></div>
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">PERSON</font></div>
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">WITH</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td style="width: 3%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 7%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;7&#160;</font></div>
        </td>
        <td style="width: 2.81%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 71%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SOLE VOTING POWER</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">0</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 3%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 7%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;8</font></div>
        </td>
        <td style="width: 2.81%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 71%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SHARED VOTING POWER</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;">3,205,559</div>
        </td>
      </tr>
      <tr>
        <td style="width: 3%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 7%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;9</font></div>
        </td>
        <td style="width: 2.81%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 71%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SOLE DISPOSITIVE POWER</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">0</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 3%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 7%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">10</font></div>
        </td>
        <td style="width: 2.81%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 71%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SHARED DISPOSITIVE POWER</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;">3,205,559</div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">11</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;">3,205,559</div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">12</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#9744;</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">13</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">7.8%</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">14</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">TYPE OF REPORTING PERSON*</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">HC, OO</font></div>
        </td>
      </tr>

  </table>
  <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
  <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%;" id="z4d9da9f307a040c58fb350813b750bd1">

      <tr>
        <td style="width: 2%; vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">*</font></div>
        </td>
        <td style="width: 98%; vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SEE INSTRUCTIONS BEFORE FILLING OUT</font></div>
        </td>
      </tr>

  </table>
  <div style="margin-top: 6pt; margin-bottom: 6pt;"><br>
  </div>
  <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
    <div style="page-break-after:always;" id="DSPFPageBreak">
      <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
  </div>
  <div style="margin-top: 6pt; margin-bottom: 6pt;"><br>
  </div>
  <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
  <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%;" id="z55d394d8e5bf48a4873c24dd3b09e08f">

      <tr>
        <td style="width: 20%; vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">CUSIP&#160;No. 695127100</font></div>
        </td>
        <td style="width: 20%; vertical-align: bottom;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td style="width: 20%; vertical-align: bottom;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">13D</font></div>
        </td>
        <td style="width: 20%; vertical-align: bottom;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td style="width: 20%; vertical-align: bottom;">&#160;</td>
      </tr>

  </table>
  <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
  <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%;" id="zcb112034f6e94a8689875845613751ed">

      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;1&#160;</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">NAME OF REPORTING PERSONS</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Mitchell Blutt</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;2</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">(a)&#160;&#160;&#9744;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;(b)&#160;&#160;&#9744;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;3</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SEC USE ONLY</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;4</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SOURCE OF FUNDS*</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">AF</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;5</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) or 2(e)</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#9744;</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;6</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">CITIZENSHIP OR PLACE OF ORGANIZATION</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">United States</font></div>
        </td>
      </tr>
      <tr>
        <td colspan="3" rowspan="4" style="vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">NUMBER&#160;OF</font></div>
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SHARES</font></div>
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">BENEFICIALLY</font></div>
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">OWNED&#160;BY</font></div>
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">EACH</font></div>
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">REPORTING</font></div>
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">PERSON</font></div>
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">WITH</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td style="width: 3%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 7%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;7&#160;</font></div>
        </td>
        <td style="width: 2.81%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 71%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SOLE VOTING POWER</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">0</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 3%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 7%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;8</font></div>
        </td>
        <td style="width: 2.81%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 71%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SHARED VOTING POWER</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;">3,205,559</div>
        </td>
      </tr>
      <tr>
        <td style="width: 3%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 7%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;9</font></div>
        </td>
        <td style="width: 2.81%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 71%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SOLE DISPOSITIVE POWER</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">0</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 3%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 7%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">10</font></div>
        </td>
        <td style="width: 2.81%; vertical-align: bottom; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;&#160;</font></div>
        </td>
        <td style="width: 71%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SHARED DISPOSITIVE POWER</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;">3,205,559</div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">11</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;">3,205,559</div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">12</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#9744;</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">13</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">7.8%</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 5%; vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">14</font></div>
        </td>
        <td style="width: 2.1%; vertical-align: bottom; border-bottom: #000000 2px solid;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td colspan="5" style="vertical-align: top; border-bottom: 2px solid rgb(0, 0, 0);">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">TYPE OF REPORTING PERSON*</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">HC, IN</font></div>
        </td>
      </tr>

  </table>
  <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
  <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%;" id="zb9614ef571a846c2bacf4ce2bceabcd3">

      <tr>
        <td style="width: 2%; vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">*</font></div>
        </td>
        <td style="width: 98%; vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">SEE INSTRUCTIONS BEFORE FILLING OUT</font></div>
        </td>
      </tr>

  </table>
  <div style="margin-top: 6pt; margin-bottom: 6pt;"><br>
  </div>
  <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
    <div style="page-break-after:always;" id="DSPFPageBreak">
      <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
  </div>
  <div style="margin-top: 6pt; margin-bottom: 6pt;"><br>
  </div>
  <div style="text-align: center; margin-top: 12pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">Amendment No. 1 to Schedule 13D</font></div>
  <div style="text-align: left; margin-top: 12pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">The following constitutes Amendment No. 1 (&#8220;Amendment No. 1&#8221;) to the Schedule 13D filed with the Securities and Exchange
      Commission (&#8220;SEC&#8221;) by Consonance Capital Management LP, a Delaware limited partnership (&#8220;Consonance&#8221;), Consonance Capman GP LLC, a Delaware limited liability company (&#8220;Capman&#8221;), and Dr.&#160;Mitchell Blutt, the principal of Consonance (collectively, the
      &#8220;Reporting Persons&#8221;) on October 22, 2018. This Amendment No. 1 amends and supplements the Schedule 13D as specifically set forth herein.</font></div>
  <div style="text-align: left; margin-top: 12pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">All capitalized terms contained herein but not otherwise defined shall have the meanings ascribed to such terms in the Schedule
      13D, as amended. Information given in response to each item shall be deemed incorporated by reference in all other items, as applicable.</font></div>
  <div style="text-align: left; margin-top: 12pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">This Schedule 13D relates to Common Stock of the Issuer (as defined below) purchased by Consonance through the accounts of
      Consonance&#8217;s private fund client and potentially through its managed account client (collectively, the &#8220;Consonance Investors&#8221;). Consonance serves as the investment manager to the Consonance Investors and may direct the vote and dispose of the </font><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">3,205,559 shares of Common Stock held by the Consonance Investors. As the general partner of Consonance, Capman may direct the vote and disposition of the 3,205,559 shares of
      Common Stock held by the Consonance Investors. As the principal of Consonance, Dr.&#160;Blutt may direct the vote and disposition of the </font><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">3,205,559 shares of Common Stock
      held by the Consonance Investors.</font></div>
  <div style="text-align: left;"><font style="font-size: 18pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
  <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%;" id="ze71a253656254e25a48255b788641723">

      <tr>
        <td style="width: 5%; vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">Item&#160;1.</font></div>
        </td>
        <td style="width: 95%; vertical-align: top;">
          <div style="text-align: left;"><u><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Security and Issuer</font></font></u></div>
        </td>
      </tr>

  </table>
  <div style="text-align: left; margin-top: 6pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Item 1 of the Schedule 13D is hereby amended and restated as follows:</font></div>
  <div style="text-align: left; margin-top: 6pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">On April 9, 2019, Pacira Pharmaceuticals, Inc. changed its name to Pacira BioSciences, Inc. (the &#8220;Issuer&#8221;).&#160; The class of equity
      security to which this statement on Schedule 13D relates is the Common Stock, par value $0.001 per share (the &#8220;Common Stock&#8221;) of the Issuer, a Delaware corporation. The address of the principal executive offices of the Issuer is 5 Sylvan Way, Suite
      300, Parsippany, New Jersey, 07054.</font></div>
  <div style="text-align: left; margin-top: 6pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;"> <br>
    </font></div>
  <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%;" id="z6188caaf447e434f883cc20f7bf9bae1">

      <tr>
        <td style="width: 5%; vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">Item&#160;4.</font></div>
        </td>
        <td style="width: 95%; vertical-align: top;">
          <div style="text-align: left;"><u><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Purpose of the Transaction</font></font></u></div>
        </td>
      </tr>

  </table>
  <div style="text-align: left; margin-top: 6pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Item 4 of Schedule 13D is supplemented and superseded, as the case may be, as follows:</font></div>
  <div style="text-align: left; margin-top: 6pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">This Amendment No. 1 is being filed to report dispositions of beneficial ownership of shares of Common Stock in an amount equal
      to one percent or more of the Issuer&#8217;s outstanding Common Stock since the Reporting Persons filed the Schedule 13D. The disclosure in Item 5(c) below regarding transactions in the Issuer&#8217;s Common Stock effected during the previous 60 days is
      incorporated by reference herein. Consistent with their investment purpose, the Reporting Persons may make, or cause, further dispositions of Common Stock from time to time and may acquire, or cause to be acquired, additional shares of Common Stock,
      in each case depending on market conditions and other factors.</font></div>
  <div style="text-align: left; margin-top: 12pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">The Reporting Persons continuously assess the Issuer&#8217;s business, financial condition, results of operations and prospects,
      general economic conditions, other developments and additional investment opportunities. Depending on such assessments, the Reporting Persons may acquire additional securities of the Issuer or new securities of the Issuer or may determine to
      purchase, sell or otherwise dispose of all or some of the Issuer&#8217;s securities beneficially owned by the Reporting Persons in the open market, as applicable, in privately negotiated transactions, in transactions directly with the Issuer or otherwise.
      Such actions will depend upon a variety of factors, including, without limitation, current and anticipated future trading prices, the financial condition, results of operations and prospects of the Issuer, alternative investment opportunities,
      general economic, financial market and industry conditions and other factors that the Reporting Persons may deem material to their investment decision.</font></div>
  <div style="text-align: left; margin-top: 12pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Except as set forth herein, the Reporting Persons do not have present plans or proposals at this time that relate to or would
      result in any of the transactions described in subparagraphs (a)&#160;through (j) of Item 4 of Schedule 13D.</font></div>
  <div style="text-align: left; margin-top: 12pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;"> <br>
    </font></div>
  <table cellspacing="0" cellpadding="0" border="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%;" id="z319075e02f964b45b530c509d8875652">

      <tr>
        <td style="width: 5%; vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;">Item&#160;5.</font></div>
        </td>
        <td style="width: 95%; vertical-align: top;">
          <div style="text-align: left;"><u><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Interest in Securities of the Issuer</font></font></u></div>
        </td>
      </tr>

  </table>
  <div style="text-align: left; margin-top: 6pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Item 5 of the Schedule 13D is hereby amended and restated as follows:</font></div>
  <div style="text-align: left; margin-top: 6pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">(a) The aggregate percentage of Common Stock reported to be beneficially owned by the Reporting Persons is based upon 41,296,937
      shares of Common Stock outstanding, which is the total number of shares of Common Stock outstanding as of April 28, 2019, as reported in the Issuer&#8217;s Form 10-Q filed with the Securities and Exchange Commission (the &#8220;SEC&#8221;) on May 2, 2019.</font></div>
  <div style="text-align: left; margin-top: 12pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Consonance, as the investment manager of the Consonance Investors, may be deemed to beneficially own the </font><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">3,205,559 shares of Common Stock held by the Consonance Investors, representing approximately 7.8% of the issued and outstanding shares of Common Stock of the Issuer.</font></div>
  <div style="text-align: left; margin-top: 12pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">In addition, Capman and Dr.&#160;Blutt, as the general partner and principal, respectively, of Consonance, the investment manager of
      the Consonance Investors, may also be deemed to beneficially own the </font><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">3,205,559 shares of Common Stock beneficially owned by the Consonance Investors, representing
      approximately 7.8% of the issued and outstanding shares of Common Stock of the Issuer.</font></div>
  <div style="text-align: left; margin-top: 12pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">The filing of this Schedule 13D shall not be construed as an admission that the Reporting Persons are, for purposes of Section
      13(d) of the Securities Exchange Act of 1934, as amended, the beneficial owners of any of the shares of Common Stock reported herein. Each of the Reporting Persons specifically disclaims beneficial ownership of the shares of Common Stock reported
      herein that are not directly owned by such Reporting Person.&#160; No Other Officer beneficially owns any shares of Common Stock of the Issuer.</font></div>
  <div style="text-align: left; margin-top: 6pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">(b) Consonance, Capman and Dr.&#160;Blutt have the shared power to vote and dispose of the Common Stock held by the Consonance
      Investors reported in this Schedule 13D.</font></div>
  <div style="text-align: left; margin-top: 6pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">(c) <font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;"><u>Annex A</u></font> attached hereto lists all
      transactions in the Common Stock during the past sixty (60)&#160;days by the Reporting Persons (on behalf of the Consonance Investors). Each of the transactions in the Common Stock were effected in the open market.</font></div>
  <div style="text-align: left; margin-top: 6pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">(d) The Consonance Investors hold the shares of Common Stock reported herein. Consonance Capital Master Account L.P. has the
      right to receive and the power to direct the receipt of dividends from, and proceeds from the sale of, more than five percent of the outstanding shares of Common Stock. Other than as set forth herein, no person other than the Reporting Persons is
      known to have the right to receive, or the power to direct the receipt of dividends from, or proceeds from the sale of, the Common Stock.</font></div>
  <div style="text-align: left; margin-top: 6pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">(e) Not applicable.</font></div>
  <div style="text-align: left;"><font style="font-size: 18pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
  <div style="text-align: left;"><font style="font-size: 18pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
  <div style="margin-top: 6pt; margin-bottom: 6pt;"><br>
  </div>
  <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
    <div style="page-break-after:always;" id="DSPFPageBreak">
      <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
  </div>
  <div style="text-align: center;"><font style="font-weight: bold; font-family: 'Times New Roman', Times, serif; font-size: 10pt;"><u>Signatures</u></font></div>
  <div style="text-align: left; margin-top: 12pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">After reasonable inquiry and to the best of their knowledge and belief, each of the undersigned certifies that the information
      set forth in this statement is true, complete and correct.</font></div>
  <div style="text-align: left; margin-top: 12pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Dated: June 5, 2019</font></div>
  <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
  <table cellspacing="0" cellpadding="0" border="0" align="center" style="width: 25%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;" id="z57491d2cc7a341669dcae2795070f88f">

      <tr>
        <td style="width: 1%; vertical-align: middle;">&#160;</td>
        <td style="width: 1%; vertical-align: bottom;">&#160;</td>
        <td style="width: 45%; vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td colspan="3" style="vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">CONSONANCE CAPITAL </font></div>
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">MANAGEMENT LP</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 1%; vertical-align: middle;">&#160;</td>
        <td colspan="2" style="vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 1%; vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">By:</font></div>
        </td>
        <td style="width: 1%; vertical-align: bottom;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td style="width: 45%; vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Consonance Capman GP LLC</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 1%; vertical-align: middle;">&#160;</td>
        <td colspan="2" style="vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 1%; vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">By:</font></div>
        </td>
        <td style="width: 1%; vertical-align: bottom;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td style="width: 45%; vertical-align: top;">
          <div>
            <div style="text-align: left;"><u><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">/s/ Mitchell Blutt</font></u></div>
          </div>
        </td>
      </tr>
      <tr>
        <td style="width: 1%; vertical-align: top;">&#160;</td>
        <td style="width: 1%; vertical-align: bottom;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td style="width: 45%; vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Mitchell Blutt</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 1%; vertical-align: top;">&#160;</td>
        <td style="width: 1%; vertical-align: bottom;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td style="width: 45%; vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Managing Member</font></div>
        </td>
      </tr>
      <tr>
        <td colspan="3" style="vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td colspan="3" style="vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">CONSONANCE CAPMAN GP LLC</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 1%; vertical-align: middle;">&#160;</td>
        <td colspan="2" style="vertical-align: middle;">&#160;</td>
      </tr>
      <tr>
        <td style="width: 1%; vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">By:</font></div>
        </td>
        <td style="width: 1%; vertical-align: bottom;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td style="width: 45%; vertical-align: top;">
          <div>
            <div style="text-align: left;"><u><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">/s/ Mitchell Blutt</font></u></div>
          </div>
        </td>
      </tr>
      <tr>
        <td style="width: 1%; vertical-align: top;">&#160;</td>
        <td style="width: 1%; vertical-align: bottom;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td style="width: 45%; vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Mitchell Blutt</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 1%; vertical-align: top;">&#160;</td>
        <td style="width: 1%; vertical-align: bottom;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
        </td>
        <td style="width: 45%; vertical-align: top;">
          <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Managing Member</font></div>
        </td>
      </tr>
      <tr>
        <td rowspan="1" style="width: 1%; vertical-align: top;">&#160;</td>
        <td rowspan="1" style="width: 1%; vertical-align: bottom;">&#160;</td>
        <td rowspan="1" style="width: 45%; vertical-align: top;">&#160;</td>
      </tr>

  </table>
  <table cellspacing="0" cellpadding="0" border="0" align="center" style="width: 25%; font-family: 'Times New Roman', Times, serif; font-size: 10pt;">

      <tr>
        <td rowspan="1" style="width: 1%; vertical-align: top;">&#160;</td>
        <td rowspan="1" style="width: 30%; vertical-align: bottom;"><u><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">/s/ Mitchell Blutt</font></u> <br>
        </td>
        <td rowspan="1" style="width: 5%; vertical-align: top;">&#160;<br>
        </td>
      </tr>
      <tr>
        <td rowspan="1" style="width: 1%; vertical-align: top;">&#160;</td>
        <td rowspan="1" style="width: 30%; vertical-align: bottom;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Mitchell Blutt</font></td>
        <td rowspan="1" style="width: 5%; vertical-align: top;">&#160;</td>
      </tr>

  </table>
  <div style="margin-top: 6pt; margin-bottom: 6pt; clear: both;"><br>
  </div>
  <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
  <br>
  <div style="clear: both; margin-top: 10pt; margin-bottom: 10pt;" id="DSPFPageBreakArea">
    <div style="page-break-after:always;" id="DSPFPageBreak">
      <hr noshade="noshade" style="margin: 4px 0px; width: 100%; border-width: 0; height: 2px; color: #000000; background-color: #000000; clear: both;"></div>
  </div>
  <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif; font-weight: bold;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;"><u>ANNEX A</u></font></font></div>
  <div style="text-align: left; margin-top: 12pt;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">The following table sets forth all transactions with respect to shares of Common Stock of the Issuer of which the Reporting
      Persons may be deemed to have beneficial ownership effected in the past 60 days.&#160;All such transactions were sales of Common Stock effected in the open market, and the table excludes commissions paid in per share prices.</font></div>
  <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">&#160;</font></div>
  <table cellspacing="0" cellpadding="0" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%;" id="z1e2a1721cb7a4ee09411a30ea2e0189e">

      <tr>
        <td style="width: 25%; vertical-align: top; background-color: #BFBFBF; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Trade Date</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; background-color: #BFBFBF; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Buy/Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; background-color: #BFBFBF; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Shares</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; background-color: #BFBFBF; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Per Share Cost</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">5/15/2019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">130,498</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$45.6271</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">5/15/2019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">32,611</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$45.6271</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">5/16/2019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">52,044</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$44.7153</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">5/16/2019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">12,996</font></div>
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        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$44.7153</font></div>
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      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">5/22/2019</font></div>
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        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">20,002</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$43.2856</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">5/22/2019</font></div>
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        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">4,998</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$43.2856</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">5/23/2019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">13,135</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$42.9760</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">5/23/2019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">3,283</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$42.9760</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">5/29/2019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">20,002</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$42.8635</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">5/29/2019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">4,998</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$42.8635</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">5/30/3019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">20,002</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$43.5909</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">5/30/2019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">4,998</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$43.5909</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">5/31/2019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">20,002</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$43.6338</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">5/31/2019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">4,998</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$43.6338</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">6/3/2019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">14,104</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$43.5252</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">6/3/2019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">34,100</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$43.4345</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">6/3/2019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">12,001</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$43.35</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">6/3/2019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">320</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$43.65</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">6/3/2019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">1,120</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$43.6336</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">6/3/2019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">3,524</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$43.5252</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">6/3/2019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">8,520</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$43.4345</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">6/3/2019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">2,999</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$43.35</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">6/3/2019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">80</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$43.65</font></div>
        </td>
      </tr>
      <tr>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">6/3/2019</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">Sell</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">280</font></div>
        </td>
        <td style="width: 25%; vertical-align: top; border-bottom: #000000 2px solid;">
          <div style="text-align: center;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;">$43.6336</font></div>
        </td>
      </tr>
      <tr>
        <td rowspan="1" style="width: 25%; vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0); text-align: center;">6/4/2019 <br>
        </td>
        <td rowspan="1" style="width: 25%; vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0); text-align: center;">Sell <br>
        </td>
        <td rowspan="1" style="width: 25%; vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0); text-align: center;">20,002 <br>
        </td>
        <td rowspan="1" style="width: 25%; vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0); text-align: center;">$42.9092 <br>
        </td>
      </tr>
      <tr>
        <td rowspan="1" style="width: 25%; vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0); text-align: center;">6/4/2019 <br>
        </td>
        <td rowspan="1" style="width: 25%; vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0); text-align: center;">Sell <br>
        </td>
        <td rowspan="1" style="width: 25%; vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0); text-align: center;">4,998 <br>
        </td>
        <td rowspan="1" style="width: 25%; vertical-align: middle; border-bottom: 2px solid rgb(0, 0, 0); text-align: center;">$42.9092 <br>
        </td>
      </tr>

  </table>
  <div><br>
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  <div style="text-align: left;"><font style="font-size: 10pt; font-family: 'Times New Roman', Times, serif;"> </font><br>
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</DOCUMENT>
</SEC-DOCUMENT>
