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ACQUISITION–RELATED (GAINS) CHARGES, PRODUCT DISCONTINUATION AND OTHER - Product Discontinuance (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2022 | Jun. 30, 2021 | Jun. 30, 2022 | Jun. 30, 2021
Restructuring Cost and Reserve [Line Items] |  |  |  |
Severance-related expenses | $ 950 | $ 0 | $ 4,065 | $ 0
Total acquisition-related charges | 3,222 | 7 | 8,630 | 7
Changes in contingent consideration |  |  | (22,351) | (988)
Total acquisition-related (gains) charges, product discontinuation and other | (18,058) | 146 | (13,721) | 2,019
Nuance Biotech Co. Ltd. |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |
Nuance Biotech Co. Ltd. agreement dissolution costs | 0 | 0 | 0 | 3,000
Flexion |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |
Changes in contingent consideration | 12,523 | 0 | 13,317 | 0
Myoscience Acquisition |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |
Changes in contingent consideration | (8,757) | 139 | (9,034) | (988)
Acquisition Related Fees |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |
Acquisition-related costs | 2,168 | 7 | 4,013 | 7
Other Restructuring |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |
Acquisition-related costs | $ 104 | $ 0 | $ 552 | $ 0

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- Definition This element represents acquisition-related costs incurred to effect a business combination which costs have been expensed during the period. Such costs include finder's fees; advisory, legal, accounting, valuation, and other professional or consulting fees; general administrative costs, including the costs of maintaining an internal acquisitions department; and may include costs of registering and issuing debt and equity securities. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 10 -Section 25 -Paragraph 23 -URI https://asc.fasb.org/extlink&oid=123586518&loc=d3e1043-128460 + Details
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- Definition Gain (loss) related to the termination of a contract between the parties. The termination may be due to many causes including early termination of a lease by a lessee, a breach of contract by one party, or a failure to perform. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -URI https://asc.fasb.org/extlink&oid=126954810&loc=d3e3602-108585 + Details
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