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FIXED ASSETS
 6 Months Ended
Jun. 30, 2022
Property, Plant and Equipment [Abstract]  
FIXED ASSETS FIXED ASSETS
Fixed assets, net, summarized by major category, consist of the following (in thousands):
June 30,December 31,
20222021
Machinery and equipment$116,364 $117,264 
Leasehold improvements60,155 59,740 
Computer equipment and software13,598 13,197 
Office furniture and equipment2,303 2,883 
Construction in progress94,332 80,557 
        Total286,752 273,641 
Less: accumulated depreciation(95,473)(85,240)
        Fixed assets, net$191,279 $188,401 
For the three months ended June 30, 2022 and 2021, depreciation expense was $6.5 million and $2.9 million, respectively. For the three months ended June 30, 2022 and 2021, there was $1.0 million and $1.1 million of capitalized interest on the construction of manufacturing sites, respectively.
For the six months ended June 30, 2022 and 2021, depreciation expense was $12.2 million and $5.8 million, respectively. For the six months ended June 30, 2022 and 2021, there was $1.8 million and $2.1 million of capitalized interest on the construction of manufacturing sites, respectively.
At June 30, 2022 and December 31, 2021, total fixed assets, net includes leasehold improvements and manufacturing process equipment located in Europe in the amount of $60.0 million and $65.4 million, respectively.
As of June 30, 2022 and December 31, 2021, the Company had asset retirement obligations of $3.1 million and $2.4 million, respectively, included in accrued expenses and other liabilities on its condensed consolidated balance sheet, for costs associated with returning leased spaces to their original condition upon the termination of certain lease agreements.