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STOCK PLANS (Tables)
6 Months Ended
Jun. 30, 2022
Stockholders' Equity Note [Abstract]  
Schedule of recognized stock-based compensation in consolidated statements of operations
The Company recognized stock-based compensation expense in the periods presented as follows (in thousands):
Three Months Ended
June 30,
Six Months Ended
June 30,
2022202120222021
Cost of goods sold$1,478 $1,465 $2,830 $2,917 
Research and development1,520 1,329 2,978 2,435 
Selling, general and administrative8,546 7,667 16,925 15,219 
        Total$11,544 $10,461 $22,733 $20,571 
Stock-based compensation from:
    Stock options$6,542 $6,552 $13,327 $13,048 
    Restricted stock units4,717 3,646 8,830 7,038 
    Employee stock purchase plan285 263 576 485 
        Total$11,544 $10,461 $22,733 $20,571 
Schedule of the company's stock option activity and restricted stock unit activity
The following tables contain information about the Company’s stock option and restricted stock unit, or RSU, activity for the six months ended June 30, 2022:
Stock Options Number of Options Weighted Average Exercise Price (Per Share)
 Outstanding at December 31, 2021
6,050,540 $49.32 
     Granted1,010,780 60.22 
     Exercised(630,413)34.80 
     Forfeited(54,215)52.41 
     Expired(13,054)85.48 
 Outstanding at June 30, 2022
6,363,638 52.39 
Restricted Stock Units Number of Units Weighted Average Grant Date Fair Value (Per Share)
Unvested at December 31, 2021
955,277 $52.85 
     Granted568,049 60.63 
     Vested(298,607)49.65 
     Forfeited(44,929)54.16 
Unvested at June 30, 2022
1,179,790 57.36 
Schedule of share-based payment award, stock options, valuation assumptions The fair values of stock options granted were estimated using the Black-Scholes option valuation model with the following weighted average assumptions:
Black-Scholes Weighted Average AssumptionSix Months Ended June 30, 2022
Expected dividend yieldNone
Risk-free interest rate2.83%
Expected volatility45.15%
Expected term of options4.92 years